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预防医学  2016, Vol. 28 Issue (11): 1123-1126,1130    
  综述 本期目录 | 过刊浏览 | 高级检索 |
青少年发病的成年型糖尿病分子机制及防治进展
仇海燕综述;张险峰审校
杭州市第一人民医院内分泌风湿免疫科,浙江杭州310000
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摘要 青少年发病的成年型糖尿病(MODY)是一种单基因突变所致的常染色体显性遗传病。其临床表现呈多样化,常被误诊为1型或2型糖尿病。MODY基因有50%的概率遗传给子代,目前已确定的MODY亚型及相关基因有13种,而一些MODY亚型在治疗上对特定的药物有高度敏感性,因此其诊断对患者家系成员预防MODY有重要指导意义。本文对MODY亚型及其相关基因的分子机制、临床表现及防治进展作一综述。
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仇海燕综述
张险峰审校
关键词 青少年发病的成年型糖尿病分子机制临床表现    
收稿日期: 2016-04-09          
中图分类号:  R587.1  
基金资助:浙江省自然科学基金(LY13H070003)
通信作者: 张险峰,E-mailzhangxianfeng@medmail.com.cn   
作者简介: 仇海燕,博士,医师,主要从事糖尿病基础研究工作
引用本文:   
仇海燕综述, 张险峰审校. 青少年发病的成年型糖尿病分子机制及防治进展[J]. 预防医学, 2016, 28(11): 1123-1126,1130.
链接本文:  
http://www.zjyfyxzz.com/CN/Y2016/V28/I11/1123
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