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预防医学  2021, Vol. 33 Issue (7): 685-688    DOI: 10.19485/j.cnki.issn2096-5087.2021.07.008
  综述 本期目录 | 过刊浏览 | 高级检索 |
维生素C降低缺血性脑卒中发病风险的研究进展
严倩倩1, 段世伟1, 蒙家嘉2,3 综述, 韩丽媛2,3 审校
1.宁波大学医学院医学遗传中心,浙江 宁波 315211;
2.中国科学院大学宁波华美医院;
3.中国科学院大学宁波生命与健康产业研究院,公共卫生与全球健康研究中心
Research progress of vitamin C reducing the risk of ischemic stroke
YAN Qianqian*, DUAN Shiwei, MENG Jiajia, HAN Liyuan
*Medical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, China
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摘要 缺血性脑卒中具有高发病率、高致残率和高死亡率的特点,目前缺乏有效的治疗方法,因此降低缺血性脑卒中的发病风险具有重要意义。研究表明维生素C能预防动脉粥样硬化,降低缺血性脑卒中的发病风险,但由于研究对象差异、维生素C含量评价方法不一致、混杂因素影响等,这一结论仍存在争议。本文从动物实验研究、临床研究和队列研究三个方面对维生素C降低缺血性脑卒中发病风险的研究结果进行综述,为后续研究提供参考。
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严倩倩
段世伟
蒙家嘉
韩丽媛
关键词 缺血性脑卒中维生素C发病风险    
Abstract:Ischemic stroke is characterized by high morbidity, disability and mortality. At present, there is a lack of effective treatment for ischemic stroke, so it is of great significance to reduce the incidence risk of ischemic stroke. Studies show that vitamin C can prevent atherosclerosis, thus reduce the incidence risk of ischemic stroke. However, this point is controversial due to the differences of study population, inconsistent evaluation methods of vitamin C content and the influence of various confounding factors. This paper reviews the related animal experiments, clinical trials and cohort studies, in order to provide reference for subsequent studies on reducing the incidence risk of ischemic stroke.
Key wordsischemic stroke    vitamin C    incidence risk
收稿日期: 2021-02-18      修回日期: 2021-04-20     
中图分类号:  R743.3  
基金资助:国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项(2018YFC1315305)
通信作者: 韩丽媛,E-mail:hanliyuan@ucas.ac.cn   
作者简介: 严倩倩,硕士在读
引用本文:   
严倩倩, 段世伟, 蒙家嘉, 韩丽媛. 维生素C降低缺血性脑卒中发病风险的研究进展[J]. 预防医学, 2021, 33(7): 685-688.
YAN Qianqian, DUAN Shiwei, MENG Jiajia, HAN Liyuan. Research progress of vitamin C reducing the risk of ischemic stroke. Preventive Medicine, 2021, 33(7): 685-688.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2021.07.008      或      http://www.zjyfyxzz.com/CN/Y2021/V33/I7/685
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