Epidemiological characteristics of hepatitis E in Shaoxing City from 2006 to 2024
LIU Mingqi1, MA Yan1, ZHENG Yingying2, CHEN Haimiao1, LI Jun1, FANG Yirong1
1. Shaoxing Center for Disease Control and Prevention, Shaoxing, Zhejiang 312000, China; 2. Shangyu District Center for Disease Control and Prevention, Shaoxing, Zhejiang 312300, China
Abstract：Objective To investigate the epidemiological characteristics of hepatitis E in Shaoxing City, Zhejiang Province from 2006 to 2024, so as to provide the evidence for the prevention and control of hepatitis E. Methods Data on hepatitis E incidence in Shaoxing City from 2006 to 2024 were collected through the Surveillance System of China Information System for Disease Control and Prevention. The epidemiological characteristics were analyzed using descriptive epidemiological methods. The trend in hepatitis E incidence was analyzed using the average annual percent change (AAPC) and annual percent change (APC). The spatial-temporal clustering characteristics of hepatitis E incidence were identified using spatial-temporal scanning analysis. Results A total of 2 408 hepatitis E cases were reported in Shaoxing City from 2006 to 2024, with an average annual reported incidence of 2.55/105. The overall trend was not statistically significant (AAPC=3.181%, P>0.05). Specifically, it showed an upward trend from 2006 to 2011 (APC=17.371%, P<0.05), a downward trend from 2011 to 2019 (APC=-12.497%, P<0.05), and an upward trend from 2019 to 2024 (APC=18.076%, P<0.05). The epidemic season of hepatitis E was from January to May, with seasonal indices of 122.09%, 118.60%, 145.02%, 129.57%, and 106.15%, respectively. The top three average annual reported incidences were identified in Zhuji City, Xinchang County, and Shengzhou City, with rates of 4.18/105, 2.85/105, and 2.74/105, respectively. The average annual reported incidence of hepatitis E was higher in males than in females (3.52/105 vs. 1.56/105, P<0.05). A relatively large number of hepatitis E cases were reported among individuals aged 40-<70 years, with 1 639 cases (68.06%). Among them, the group aged 60-<70 years had the highest average annual reported incidence of hepatitis E, at 4.92/105. Farmers constituted the predominant occupational group, accounting for 1 515 cases (62.92%). Spatial-temporal scanning analysis identified two clusters in Shaoxing City from 2006 to 2024. The class Ⅰ cluster was located in Shengzhou City, with aggregation time from January 1, 2011 to May 1, 2014. The class Ⅱ cluster was located in Xinchang County, with aggregation time from December 1, 2012 to March 31, 2013. Conclusions The reported incidence of hepatitis E in Shaoxing City from 2006 to 2024 exhibited a pattern of an initial increase, followed by a decrease, and then a subsequent rise. The disease demonstrated higher prevalence during the winter and spring seasons. Key populations for targeted control and prevention include males, individuals aged 40-<70 years, and farmers. Shengzhou City and Xinchang County were identified as high-risk areas.
刘明奇, 马岩, 郑莹颖, 陈海苗, 李军, 方益荣. 2006—2024年绍兴市戊型病毒性肝炎流行特征[J]. 预防医学, 2025, 37(11): 1155-1159.
LIU Mingqi, MA Yan, ZHENG Yingying, CHEN Haimiao, LI Jun, FANG Yirong. Epidemiological characteristics of hepatitis E in Shaoxing City from 2006 to 2024. Preventive Medicine, 2025, 37(11): 1155-1159.
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