Epidemiological characteristics of colorectal cancer in cancer registration areas of Guangdong Province in 2020
ZHANG Ying1, CHEN Yixuan1, GAO Yue2, WANG Ye2, LI Jiansen2, HAN Yutong2, WEI Wenqiang2,3, LIAO Yu2
1. School of Public Health, Guangdong Pharmaceutical University, Guangzhou, Guangdong 510310, China; 2. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong 511430, China; 3. National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Abstract：Objective To investigate characteristics of colorectal cancer incidence and mortality in registration areas of Guangdong Province in 2020, so as to provide a basis for optimizing regional prevention and control strategies. Methods Data on incidence and mortality of colorectal cancer in cancer registration areas of Guangdong Province in 2020 were collected from the Cancer Follow-up Registration System and the All-Cause Mortality Registration Reporting System of the Guangdong Provincial Center for Disease Control and Prevention. The crude incidence, crude mortality, truncated rate for 35 to 64 years, and cumulative rate for 0 to 64 years were calculated, and standardized using the Segi's world standard population. Descriptive epidemiological methods were applied to analyze the characteristics of colorectal cancer incidence and mortality by different genders, urban/rural areas and ages. Results A total of 14 771 cases of colorectal cancer were reported in Guangdong Province in 2020. The crude incidence, world population-standardized incidence, truncated incidence for 35 to 64 years and cumulative incidence for 0 to 64 years were 35.18/105, 24.84/105, 38.87/105 and 1.37%, respectively. A total of 5 384 deaths of colorectal cancer were reported, with crude incidence, world population-standardized incidence, truncated incidence for 35 to 64 years and cumulative incidence for 0 to 64 years were 14.55/105, 8.83/105, 10.39/105 and 0.37%, respectively. The crude incidence and mortality were higher in males than in females (40.35/105 vs. 29.88/105, 16.51/105 vs. 12.54/105, both P<0.05). The crude incidence and mortality were higher in urban areas than in rural areas (38.94/105 vs. 26.10/105, 16.60/105 vs. 10.42/105, both P<0.05). The crude incidence of colorectal cancer initially increased with advancing age (P<0.05), reaching a peak of 239.36/105 in the 80-<85 age group, followed by a marked decline after 85 years. The crude mortality of colorectal cancer increased with advancing age (P<0.05), reaching a peak of 174.25/105 in the ≥85 years age group. Conclusions In 2020, the incidence and mortality of colorectal cancer in registration areas of Guangdong Province were higher than the national averages. There were differences in the characteristics of incidence and mortality among genders, urban/areas and age. Therefore, it is necessary to strengthen the comprehensive prevention and control efforts for colorectal cancer in males, urban areas, and the elderly population.
张莹, 陈伊绚, 高玥, 王晔, 李剑森, 韩毓桐, 魏文强, 廖羽. 2020年广东省肿瘤登记地区结直肠癌流行特征分析[J]. 预防医学, 2025, 37(10): 997-1001.
ZHANG Ying, CHEN Yixuan, GAO Yue, WANG Ye, LI Jiansen, HAN Yutong, WEI Wenqiang, LIAO Yu. Epidemiological characteristics of colorectal cancer in cancer registration areas of Guangdong Province in 2020. Preventive Medicine, 2025, 37(10): 997-1001.
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