Characteristics of malignant tumor incidence and mortality in cancer registration areas of Sichuan Province in 2021
CHENG Shuwen1, DONG Ting1, ZHANG Xin1, LI You1, JI Kui1, LI Yuanqiong2, YUAN Zhipei1
1. Sichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan 610041, China; 2. Ganzi Tibetan Autonomous Prefecture Center for Disease Control and Prevention, Ganzi, Sichuan 626000, China
Abstract：Objective To investigate the characteristics of malignant tumor incidence and mortality in cancer registration areas of Sichuan Province in 2021. Methods Cancer registration data from 142 registries in Sichuan Province in 2021 were collected via the China Cancer Registry Platform. Crude incidence and crude mortality were calculated. The Chinese population-standardized incidence and world population-standardized incidence were standardized using the age structure of the standard population from the Fifth National Population Census in 2000 and Segi's world standard population. Descriptive analyses examined the distribution of rates by genders, urban/rural areas, and ages, and the ranking of leading cancer sites. Results In 2021, there were 248 600 new malignant tumor cases reported in Sichuan Province, with a crude incidence of 296.37/105. The Chinese population-standardized incidence and world population-standardized incidence were 164.67/105 and 160.47/105, respectively. There were 158 673 malignant tumor deaths, with a crude mortality of 189.16/105. The Chinese population-standardized mortality and world population-standardized mortality were 92.47/105 and 92.00/105, respectively. The Chinese population-standardized incidence and mortality in males were higher than in females (179.56/105 vs. 151.62/105, 125.09/105 vs. 60.35/105). The Chinese population-standardized incidence and mortality in urban areas were higher than in rural areas (175.74/105 vs. 157.54/105, 93.63/105 vs. 91.82/105). Both the crude incidence and crude mortality increased with age. The top ten malignant tumors by crude incidence were lung cancer, colorectal cancer, liver cancer, breast cancer, esophageal cancer, gastric cancer, cervical cancer, prostate cancer, thyroid cancer, and corpus uteri cancer, accounting for 76.33% of all new cases. The top ten by crude mortality were lung cancer, liver cancer, esophageal cancer, colorectal cancer, gastric cancer, breast cancer, pancreatic cancer, cervical cancer, prostate cancer, and brain tumors, accounting for 82.39% of all cancer deaths. Conclusions In registration areas of Sichuan Province, the incidence and mortality of malignant tumors are relatively low. Key populations such as males, urban residents, and the elderly require focused prevention and control efforts. Comprehensive measures should be prioritized for malignant tumors including lung cancer, liver cancer, esophageal cancer, gastric cancer, colorectal cancer, and breast cancer.
成姝雯, 董婷, 张新, 李尤, 季奎, 李元琼, 袁芝佩. 2021年四川省肿瘤登记地区恶性肿瘤发病和死亡特征分析[J]. 预防医学, 2025, 37(10): 1002-1008.
CHENG Shuwen, DONG Ting, ZHANG Xin, LI You, JI Kui, LI Yuanqiong, YUAN Zhipei. Characteristics of malignant tumor incidence and mortality in cancer registration areas of Sichuan Province in 2021. Preventive Medicine, 2025, 37(10): 1002-1008.
[1] BRAY F,LAVERSANNE M,WEIDERPASS E,et al.The ever-increasing importance of cancer as a leading cause of premature death worldwide[J].Cancer,2021,127(16):3029-3030. [2] BRAY F,LAVERSANNE M,SUNG H,et al.Global cancer statistics 2022:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2024,74(3):229-263. [3] 郑荣寿,陈茹,韩冰峰,等.2022年中国恶性肿瘤流行情况分析[J].中华肿瘤杂志,2024,46(3):221-231. ZHENG R S,CHEN R,HAN B F,et al.Cancer incidence and mortality in China,2022[J].Chin J Oncol,2024,46(3):221-231.(in Chinese) [4] 祁冰洁,曾晶,胥馨尹,等.2019—2022年四川省居民死因监测数据分析[J].现代预防医学,2023,50(24):4429-4433,4445. QI B J,ZENG J,XU X Y,et al.Surveillance for death causes in residents,Sichuan,2019-2022[J].Mod Prev Med,2023,50(24):4429-4433,4445.(in Chinese) [5] 祁冰洁,曾晶,邓颖,等.2017—2022年四川省居民恶性肿瘤死因及潜在寿命损失分析[J].中国肿瘤,2025,34(1):37-42. QI B J,ZENG J,DENG Y,et al.Analysis on the causes of death and potential life loss of malignant tumors in Sichuan Province from 2017 to 2022[J].China Cancer,2025,34(1):37-42.(in Chinese) [6] BRAY F,GUILLOUX A,SANKILA R,et al.Practical implications of imposing a new world standard population[J].Cancer Causes Control,2002,13(2):175-182. [7] 国家癌症中心.中国肿瘤登记工作指导手册(2016)[M].北京:人民卫生出版社,2016. National Cancer Center.Chinese guideline for cancer registration(2016)[M].Beijing:People's Medical Publishing House,2016.(in Chinese) [8] LARSEN I K,SMASTUEN M,JOHANNESEN T B,et al.Data quality at the Cancer Registry of Norway:an overview of comparability,completeness,validity and timeliness[J].Eur J Cancer,2009,45(7):1218-1231. [9] 成姝雯,董婷,袁芝佩,等.2019年四川省肿瘤登记地区不同经济区恶性肿瘤发病和死亡分析[J].中国肿瘤,2024,33(10):834-840. CHENG S W,DONG T,YUAN Z P,et al.Cancer incidence and mortality in different economic areas of Sichuan cancer registration areas in 2019[J].China Cancer,2024,33(10):834-840.(in Chinese) [10] 赫捷,魏文强.2022中国肿瘤登记年报[M].北京:人民卫生出版社,2025. HE J,WEI W Q.China cancer registry annual report 2022[M].Beijing:People's Medical Publishing House,2025.(in Chinese) [11] 国家统计局.中国统计年鉴2024[M].北京:中国统计出版社,2024. National Bureau of Statistics of China.China statistical yearbook,2024[M].Beijing:China Statistics Press,2024.(in Chinese) [12] 四川省卫生健康委员会. 2020年四川省卫生健康事业发展统计公报[EB/OL].[2025-09-18].https://wsjkw.sc.gov.cn/scwsjkw/njgb/2021/3/18/3708f81e78584f5b8a5ca4a1872c033b.shtml. [13] 吴先萍,胥馨尹,邓颖.四川省慢性病与营养监测报告2018[M].成都:电子科技大学出版社,2022. WU X P,XU X Y,DENG Y.Report on chronic disease and nutrition surveillance in Sichuan,2018[M].Chengdu:Chengdu University of Electronic Science and Technology Press,2022.(in Chinese) [14] 季芝强,胡贵平,贾光.致癌性重金属与类金属所致职业性肿瘤研究与展望[J].中国职业医学,2024,51(5):481-487,495. JI Z Q,HU G P,JIA G.Research and prospect on carcinogenic heavy metals and metalloids-induced occupational tumors[J].China Occup Med,2024,51(5):481-487,495.(in Chinese) [15] 师金,梁迪,李道娟,等.中国城市癌症早诊早治项目筛查依从性及影响因素研究[J].中国肿瘤,2021,30(8):591-599. SHI J,LIANG D,LI D J,et al.Research on the screening compliance and influencing factors of cancer screening program in urban China[J].China Cancer,2021,30(8):591-599.(in Chinese) [16] 成姝雯,董婷,张新,等. 2016年四川省肿瘤登记地区恶性肿瘤发病和死亡情况分析[J].肿瘤预防与治疗,2021,34(7):604-610. CHENG S W,DONG T,ZHANG X,et al.Analysis of cancer incidence and mortality in registration areas of Sichuan,2016[J]. J Cancer Control Treat,2021,34(7):604-610.(in Chinese) [17] 袁芝佩,王丹,成姝雯,等.2019年四川省肿瘤登记地区恶性肿瘤发病与死亡及2015—2019年变化趋势分析[J].中国肿瘤,2024,33(7):515-522. YUAN Z P,WANG D,CHENG S W,et al.Cancer incidence and mortality in Sichuan cancer registration areas in 2019 and its trend from 2015 to 2019[J].China Cancer,2024,33(7):515-522.(in Chinese) [18] 初里楠,董奕,李竹,等.2014—2021年西城区恶性肿瘤死亡及减寿分析[J].预防医学,2023,35(5):410-414. CHU L N,DONG Y,LI Z,et al.Death and life loss of malignant tumors in Xicheng District from 2014 to 2021[J].China Prev Med J,2023,35(5):410-414.(in Chinese)
