2014—2020年安徽省肿瘤登记地区食管癌发病和死亡趋势分析

doi:10.19485/j.cnki.issn2096-5087.2025.10.004

预防医学

2025, Vol. 37

Issue (10): 991-996 DOI: 10.19485/j.cnki.issn2096-5087.2025.10.004

肿瘤流行病学专题

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2014—2020年安徽省肿瘤登记地区食管癌发病和死亡趋势分析

朱强, 戴丹, 孟庆联, 吕逸丽, 窦连杰, 窦婷婷, 王华东

安徽省疾病预防控制中心,安徽合肥 230601

Trends in incidence and mortality of esophageal cancer in cancer registration areas of Anhui Province from 2014 to 2020

ZHU Qiang, DAI Dan, MENG Qinglian, LÜ Yili, DOU Lianjie, DOU Tingting, WANG Huadong

Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui 230601, China

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摘要目的分析2014—2020年安徽省肿瘤登记地区食管癌发病和死亡趋势,为完善食管癌防控措施提供依据。方法通过安徽省肿瘤登记处收集2014—2020年安徽省食管癌发病和死亡资料,计算粗发病率和粗死亡率;采用2000年第五次全国人口普查标准人口年龄构成计算中国人口标化率（中标率）;采用平均年度变化百分比（AAPC）分析不同性别、城乡和年龄食管癌发病和死亡趋势。结果安徽省食管癌发病顺位从2014年的第三位下降至2020年的第六位,粗发病率和中标发病率分别从28.74/10万和20.74/10万下降至19.23/10万和10.59/10万（AAPC=-5.846%、-9.658%,均P<0.05）;2014年和2020年食管癌死亡顺位均为第四位,粗死亡率和中标死亡率分别从19.96/10万和14.09/10万下降至16.00/10万和8.41/10万（AAPC=-3.542%、-7.784%,均P<0.05）。男性、女性、城市和农村食管癌中标发病率（AAPC=-9.682%、-9.188%、-6.175%和-12.575%,均P<0.05）和中标死亡率（AAPC=-7.734%、-7.447%、-5.366%和-10.209%,均P<0.05）呈下降趋势。2014—2020年安徽省食管癌粗发病率和粗死亡率均随年龄增长而上升;40~<50岁、50~<60岁、60~<70岁、70~<80岁组食管癌粗发病率（AAPC=-12.779%、-11.701%、-11.955%和-7.198%,均P<0.05）和粗死亡率（AAPC=-12.255%、-11.120%、-10.985%和-5.751%,均P<0.05）呈下降趋势;≥80岁组粗发病率（AAPC=-6.334%,P<0.05）呈下降趋势,粗死亡率趋势无统计学意义（P>0.05）。结论 2014—2020年安徽省肿瘤登记地区食管癌发病和死亡均呈下降趋势,应重点关注中老年人群,强化控烟限酒等健康生活行为。

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	王华东

关键词 ：食管癌, 发病率, 死亡率, 平均年度变化百分比, 安徽省

Abstract：Objective To investigate the trends in incidence and mortality of esophageal cancer in cancer registration areas of Anhui Province from 2014 to 2020, so as to provide the basis for formulating prevention and control measures. Methods The incidence and mortality data of esophageal cancer in Anhui Province from 2014 to 2020 was collected through the Cancer Registry in Anhui Province. The crude incidence and crude mortality were calculated. The Chinese population-standardized rate was standardized using the age structure of the standard population from the Fifth National Population Census in 2000. The trends in incidence and mortality of esophageal cancer were analyzed using the average annual percent change (APPC), stratified by genders, urban/rural areas, and ages. Results In Anhui Province, the rank of esophageal cancer incidence dropped from the third in 2014 to the sixth in 2020. Concurrently, the crude incidence and Chinese population-standardized incidence declined from 28.74/10⁵ and 20.74/10⁵ to 19.23/10⁵ and 10.59/10⁵, respectively (AAPC=-5.846%, -9.658%, both P<0.05). The mortality rank remained stable at the fourth in 2014 and 2020, while the crude mortality and Chinese population-standardized mortality decreased from 19.96/10⁵ and 14.09/10⁵ to 16.00/10⁵ and 8.41/10⁵, respectively (AAPC=-3.542%, -7.784%, both P<0.05). The Chinese population-standardized incidence (AAPC=-9.682%, -9.188%, -6.175% and -12.575%, all P<0.05) and Chinese population-standardized mortality (AAPC=-7.734%. -7.447%. -5.366% and -10.209%, all P<0.05) showed declining trends in males, females, urban, and rural areas, respectively. From 2014 to 2020 in Anhui Province, the crude incidence and mortality of esophageal cancer generally increased with age. However, significant declining trends were observed in crude incidence (AAPC=-12.779%, -11.701%, -11.955% and -5.751%, all P<0.05) and crude mortality (AAPC=-12.255%, -11.120%, -10.985% and -5.751%, all P<0.05) for the age groups of 40-<50, 50-<60, 60-<70, 70-<80 years. A significant declining trend in crude incidence was also seen in the ≥80 years group (APPC=-6.334%, P<0.05), but the trend in crude mortality was no statistically significant (P>0.05). Conclusion In registration areas of Anhui Province, the incidence and mortality of esophageal cancer exhibited a declining trend from 2014 to 2020, calling for focused attention on the middle-aged and elderly population and enhanced health behaviors such as tobacco and alcohol control.

Key words： esophageal cancer incidence mortality average annual percent change Anhui Province

收稿日期: 2025-08-18 修回日期: 2025-09-23

中图分类号:

R735.1

基金资助:安徽省疾病预防控制中心（安徽省公共卫生研究院）青年科研项目（JKQN20230106）

作者简介: 朱强,硕士,主要从事慢性病预防与控制研究工作

通信作者: 王华东,E-mail：wanghuadong@ahcdc.com.cn

引用本文:

朱强, 戴丹, 孟庆联, 吕逸丽, 窦连杰, 窦婷婷, 王华东. 2014—2020年安徽省肿瘤登记地区食管癌发病和死亡趋势分析[J]. 预防医学, 2025, 37(10): 991-996.
ZHU Qiang, DAI Dan, MENG Qinglian, LÜ Yili, DOU Lianjie, DOU Tingting, WANG Huadong. Trends in incidence and mortality of esophageal cancer in cancer registration areas of Anhui Province from 2014 to 2020. Preventive Medicine, 2025, 37(10): 991-996.

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