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预防医学  2025, Vol. 37 Issue (9): 865-869    DOI: 10.19485/j.cnki.issn2096-5087.2025.09.001
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基于组轨迹模型的老年人膳食多样性与认知功能研究
董春玲1,2, 王冲3, 关添元2, 刘玥2, 李雪莹2, 张玉海2
1.陕西中医药大学公共卫生学院,陕西 咸阳 712046;
2.空军军医大学军事预防医学系军队卫生统计学教研室,特殊作业环境危害评估与防治教育部重点实验室,陕西 西安 710032;
3.陕西中医药大学医学科研实验中心,陕西 咸阳 712046
Association between dietary diversity and cognitive function among the elderly based on group-based trajectory model
DONG Chunling1,2, WANG Chong3, GUAN Tianyuan2, LIU Yue2, LI Xueying2, ZHANG Yuhai2
1. School of Public Health, Shaanxi University of Chinese Medicine, Xianyang, Shannxi 712046, China;
2. Department of Military Health Statistics, Faculty of Military Preventive Medicine, Air Force Medical University, Key Laboratory of Hazard Assessment and Control in Special Operational Environment, Ministry of Education, Xi'an, Shannxi 710032, China;
3. Medical Research Experimental Center, Shaanxi University of Chinese Medicine, Xianyang, Shannxi 712046, China
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摘要 目的 应用组轨迹模型分析老年人膳食多样性与认知功能的关系,为制定膳食预防认知功能损伤策略提供依据。方法 基于中国老年健康影响因素跟踪调查(CLHLS)项目,收集2008—2018年≥65岁老年人的人口学信息、生活行为、心理幸福感和日常生活活动能力等资料。采用食物频率问卷调查膳食多样性,<7分判定为低膳食多样性。采用中文版简易精神状态检查表评估认知功能,以2008—2018年认知功能得分建立组轨迹模型,分析认知功能变化轨迹;采用无序多分类logistic回归模型分析膳食多样性与认知功能的关联。结果 收集1 613人资料,年龄MQR)为72.00(10.00)岁。男性810人,占50.22%;女性803人,占49.78%。组轨迹模型分析结果分为低水平正常组、高水平正常组和先慢后快下降组,分别为796、585和232人,占49.35%、36.27%和14.38%;其中低膳食多样性分别为497、311和166人,占62.44%、53.16%和71.55%,差异有统计学意义(P<0.05)。无序多分类logistic回归分析结果显示,调整人口学信息、生活行为、心理幸福感和日常生活活动能力后,先慢后快下降组与高水平正常组比较,低膳食多样性(OR=1.622,95%CI:1.103~2.384)与老年人认知功能存在统计学关联。结论 低膳食多样性可能增加老年人认知功能损伤风险。
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董春玲
王冲
关添元
刘玥
李雪莹
张玉海
关键词 认知功能膳食多样性老年人组轨迹模型    
AbstractObjective To analyze the association between dietary diversity and cognitive function among the elderly using group-based trajectory model, so as to provide the basis for formulating dietary intervention strategies to prevent cognitive impairment. Methods Based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS) project, demographic information, lifestyle behaviors, psychological well-being, and activities of daily living of elderly individuals aged ≥65 years from 2008 to 2018 were collected. Dietary diversity was assessed using a food frequency questionnaire, with a score of <7 points defined as low dietary diversity. Cognitive function was evaluated using the Chinese version of the Mini-Mental State Examination (MMSE). A group-based trajectory model was established based on cognitive function scores from 2008 to 2018 to analyze the trajectories of cognitive function change. The association between dietary diversity and cognitive function was analyzed using a multinomial logistic regression model. Results A total of 1 613 individuals were collected, with a median age was 72.00 (interquartile range, 10.00) years. There were 810 males (50.22%) and 803 females (49.78%). The group-based trajectory model analysis categorized the participants into three groups: the low-level normal group, the high-level normal group, and the slow-then-rapid decline group, comprising 796 (49.35%), 585 (36.27%), and 232 (14.38%) individuals, respectively. Among these groups, the numbers of individuals with low dietary diversity were 497 (62.44%), 311 (53.16%), and 166 (71.55%), respectively, with a statistically significant difference (P<0.05). Multinomial logistic regression analysis showed that after adjusting for demographic information, lifestyle behaviors, psychological well-being, and activities of daily living, compared with the high-level normal group, low dietary diversity was statistically associated with cognitive function in the slow-then-rapid decline group (OR=1.622, 95%CI: 1.103-2.384). Conclusion Low dietary diversity may increase the risk of cognitive impairment among the elderly.
Key wordscognitive function    dietary diversity    the elderly    group-based trajectory model
收稿日期: 2025-05-23      修回日期: 2025-08-03      出版日期: 2025-09-10
中图分类号:  R195  
基金资助:国家自然科学基金项目(82473726,82073662)
作者简介: 董春玲,硕士研究生在读,公共卫生专业
通信作者: 张玉海,E-mail:zhyh@fmmu.edu.cn   
引用本文:   
董春玲, 王冲, 关添元, 刘玥, 李雪莹, 张玉海. 基于组轨迹模型的老年人膳食多样性与认知功能研究[J]. 预防医学, 2025, 37(9): 865-869.
DONG Chunling, WANG Chong, GUAN Tianyuan, LIU Yue, LI Xueying, ZHANG Yuhai. Association between dietary diversity and cognitive function among the elderly based on group-based trajectory model. Preventive Medicine, 2025, 37(9): 865-869.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2025.09.001      或      http://www.zjyfyxzz.com/CN/Y2025/V37/I9/865
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