Abstract：Objective To explore the association between coffee intake and all cancer mortality in East Asian populations. Methods We searched literatures which assessed the relationship between coffee intake and cancer mortality in Asian populations published by December 10th,2018 from China National Knowledge Infrastructure,Wanfang Database,VIP Database and PubMed. We conducted category and dose-response meta-analyses using Stata 15.0. Results A total of 335 relevant articles were retrieved; five articles were finally included in the meta-analyses,of which four were carried out in Japanese population and one in Singaporean Chinese population. The total sample size of the five articles was 361 802,and the number of deaths from cancer was 17 664. The results showed that coffee intake reduced the risk of all cancer mortality in East Asian populations（RR=0.93,95%CI：0.87-0.99）. There was no statistical significant association between coffee intake and all cancer mortality in East Asian men（RR=0.94,95%CI：0.77-1.15）. Among East Asian women,coffee consumption reduced the risk of all cancer mortality by 12%（RR=0.88,95%CI：0.81-0.95）. All cancer mortality risk decreased with the increase of coffee intake,and reached the lowest point at one and a half cups of coffee per day（RR=0.92,95%CI：0.86-0.98）. Conclusion Coffee intake reduced the risk of all cancer mortality in East Asian populations,which was obviously found in East Asian women. Drinking one and a half cups of coffee a day had the lowest risk of all cancer mortality.
李迎君, 朱家豪, 范佳耀, 范春红. 咖啡摄入与东亚人群恶性肿瘤死亡风险关联的Meta分析[J]. 预防医学, 2019, 31(6): 549-553.
LI Ying-jun, ZHU Jia-hao, FAN Jia-yao, FAN Chun-hong. Meta-analysis of coffee intake and all cancer mortality in East Asian population. Preventive Medicine, 2019, 31(6): 549-553.
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