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预防医学  2026, Vol. 38 Issue (9): 903-906    DOI: 10.19485/j.cnki.issn2096-5087.2026.09.009
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结核病病例主动发现策略的卫生经济学评价研究进展
杨静, 李佳芮, 牟芷若 综述, 汪清雅 审校
重庆市结核病防治所,重庆 400050
Research progress on health economic evaluation of active case finding strategies for tuberculosis
YANG Jing, LI Jiarui, MOU Zhiruo, WANG Qingya
Chongqing Department of Tuberculosis Control and Prevention, Chongqing 400050, China
全文: PDF(871 KB)  
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摘要 结核病是由结核分枝杆菌引起的慢性感染性疾病,可累及全身多个脏器。病例主动发现(ACF)策略是提高重点人群结核病发现水平的重要手段。本文检索PubMed、中国知网等数据库收录的结核病ACF策略卫生经济学评价文献,围绕ACF策略的成本效果和成本效益评价,对不同重点人群ACF策略的卫生经济学证据进行综述。现有证据表明,ACF策略在重点人群中可能具有经济学价值,其中肺结核患者密切接触者和部分艾滋病病毒感染者的成本效果较突出,老年人群和聚集性场所人群的相关证据较有限。ACF策略的经济学价值受目标人群、筛查方法和卫生资源条件等因素影响。目前研究多关注单个病例检出成本,缺乏对长期健康收益和社会经济效益的综合评价。未来应加强不同人群和筛查策略的真实世界卫生经济学研究,为优化结核病防控策略和资源配置提供循证依据。
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杨静
李佳芮
牟芷若 综述
汪清雅 审校
关键词 : 结核病,  病例主动发现,  卫生经济学评价    
Abstract:Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis, which can involve multiple organs throughout the body. The active case finding (ACF) strategy is an important approach for improving TB case detection among priority populations. In this review, literature on health economic evaluations of TB ACF strategies included in PubMed, CNKI and other databases was retrieved, and the health economic evidence of ACF strategies among different priority populations was reviewed, focusing on cost-effectiveness and cost-benefit assessments. Existing evidence indicates that ACF strategies may hold economic value in priority populations, with relatively prominent cost-effectiveness among close contacts of pulmonary tuberculosis patients and certain individuals living with HIV, whereas the evidence for elderly populations and populations in congregate settings remains relatively limited. The economic value of ACF strategies is influenced by target populations, screening methods, health resource conditions and other factors. Currently, most studies concentrate on the cost per case detected, lacking comprehensive evaluations of long-term health benefits and socioeconomic benefits. Future real-world health economic research across different populations and screening strategies should be strengthened, so as to provide the evidence for optimizing TB prevention and control strategies and resource allocation.
Key words: tuberculosis    active case finding    health economic evaluation
收稿日期: 2026-03-12      修回日期: 2026-08-04     
中图分类号:  R52  
作者简介: 杨静,硕士,医师,主要从事结核病监测工作
通信作者: 汪清雅,E-mail:15902381223@126.com   
引用本文:   
杨静, 李佳芮, 牟芷若 综述, 汪清雅 审校. 结核病病例主动发现策略的卫生经济学评价研究进展[J]. 预防医学, 2026, 38(9): 903-906.
YANG Jing, LI Jiarui, MOU Zhiruo, WANG Qingya. Research progress on health economic evaluation of active case finding strategies for tuberculosis. Preventive Medicine, 2026, 38(9): 903-906.
链接本文:  
https://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2026.09.009      或      https://www.zjyfyxzz.com/CN/Y2026/V38/I9/903
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