Disease burden of leukemia in Jiangsu Province from 1990 to 2019
MA Zhaojun1, LI Weiwei1, DONG Jianmei1, ZHOU Jinyi2, HAN Renqiang2, QIN Xucheng1
1. Department of Chronic Non-communicable Diseases Control and Prevention, Lianyungang Center for Disease Control and Prevention, Lianyungang, Jiangsu 222003, China; 2. Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210029, China
Abstract：Objective To investigate the trends in the disease burden of leukemia in Jiangsu Province from 1990 to 2019, so as to provide insights into leukemia control in Jiangsu Province. Methods The prevalence, incidence, death and disability adjusted life years (DALYs) of leukemia in Jiangsu Province from 1990 to 2019 were retrieved from the 2019 Global Burden of Disease Study (GBD 2019) database, and standardized by the age structure of Chinese populations in 2000. The trends in the disease burden of leukemia in Jiangsu Province from 1990 to 2019 were analyzed using average annual percent change (AAPC). Results The average annual standardized prevalence, incidence, mortality and DALY rate of leukemia were 63.63/105, 9.76/105, 4.10/105 and 194.83/105 in Jiangsu Province from 1990 to 2019, respectively. The average annual standardized prevalence (AAPC=1.420%, t=5.644, P<0.001) and incidence (AAPC=0.806%, t=3.505, P<0.001) of leukemia appeared a tendency towards a rise, while the average annual standardized mortality (AAPC=-1.589%, t=-14.714, P<0.001) and DALY rate (AAPC=-1.849%, t=-9.046, P<0.001) of leukemia appeared a tendency towards a decline in Jiangsu Province from 1990 to 2019. Higher average annual standardized prevalence (65.27/105 vs. 62.38/105, P<0.001), incidence (10.32/105 vs. 9.29/105, P<0.001), mortality (4.69/105 vs. 3.57/105, P<0.001) and DALY rate of leukemia (216.94/105 vs. 172.80/105, P<0.001) were estimated among men than among women. The crude prevalence of leukemia peaked among patients at ages of 0 to 14 years and 60 to 74 years, and the crude incidence, DALY rate and mortality of leukemia peaked at ages of 0 to 14 years and 75 years and older. Conclusions The mortality and DALY of leukemia appeared a tendency towards a decline and the prevalence and incidence appeared a tendency towards a rise in Jiangsu Province from 1990 to 2019; however, there were high disease burdens of leukemia among men, children and the elderly.
马昭君, 李伟伟, 董建梅, 周金意, 韩仁强, 秦绪成. 1990—2019年江苏省白血病疾病负担分析[J]. 预防医学, 2023, 35(4): 282-285,290.
MA Zhaojun, LI Weiwei, DONG Jianmei, ZHOU Jinyi, HAN Renqiang, QIN Xucheng. Disease burden of leukemia in Jiangsu Province from 1990 to 2019. Preventive Medicine, 2023, 35(4): 282-285,290.
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