Influencing factors for cognitive function among aluminum workers based on a quantile regression model
XIN Yulu1, LI Mujia1, DING Xiaohui1, LU Yang1, LI Wenjing1, WANG Linping1,2,3, LU Xiaoting1,2,3, SONG Jing1,2,3
1. School of Public Health, Shanxi Medical University, Taiyuan, Shanxi 030001, China; 2. Key Laboratory of Coal Environmental Diseases and Control, Ministry of Education, Taiyuan, Shanxi 030001, China; 3. Shanxi Key Laboratory of Environmental Hazard Factors and Population Health, Taiyuan, Shanxi 030001, China
Abstract：Objective To investigate the influencing factors for cognitive function among aluminum workers, so as to provide the basis for intervention and prevention of cognitive function among aluminum-exposed populations. Methods From July to August 2019, male aluminum workers in the electrolytic aluminum workshop of an aluminum factory in Shanxi Province were selected using the cluster sampling method. Demographic information, prevalence of chronic diseases, lifestyle behaviors, night shifts, and sleep quality were collected through questionnaire surveys. Blood aluminum levels were measured using inductively coupled plasma-mass spectrometry. Cognitive function was investigated using the Montreal Cognitive Assessment. Factors affecting cognitive function among aluminum workers were analyzed by a quantile regression model. Results A total of 142 aluminum workers were surveyed, including 57 workers aged 20 to <40 years (40.14%) and 85 workers aged 40 to 60 years (59.86%). The median blood aluminum level was 38.23 (interquartile range, 21.82) μg/L. The median cognitive function score was 24.00 (interquartile range, 3.00) points. Quantile regression analysis revealed that older age (βQ5=-0.186, 95%CI: -0.269 to -0.102), lower educational level (βQ5=1.933, 95%CI: 1.029 to 2.838; βQ10=1.743, 95%CI: 0.480 to 3.006; βQ50=1.038, 95%CI: 0.141 to 1.935; βQ75=1.006, 95%CI: 0.437 to 1.575; βQ90=1.111, 95%CI: 0.291 to 1.930), smoking (βQ5=-2.056, 95%CI: -3.264 to -0.849), alcohol consumption (βQ5=-1.821, 95%CI: -3.247 to -0.396) and higher blood aluminum level (βQ5=-0.075, 95%CI: -0.110 to -0.040; βQ10=-0.078, 95%CI: -0.127 to -0.029; βQ50=-0.075, 95%CI: -0.110 to -0.040; βQ75=-0.057, 95%CI: -0.079 to -0.035; βQ90=-0.067, 95%CI: -0.099 to -0.035) were associated with cognitive function decline among aluminum workers. Conclusions Educational level and blood aluminum level are the main factors affecting the cognitive function among aluminum workers. Among those with lower cognitive function scores, age, smoking and alcohol consumption are also associated with cognitive function.
辛宇璐, 李沐家, 丁晓慧, 卢炀, 李文静, 王林平, 路小婷, 宋静. 基于分位数回归模型的铝作业工人认知功能影响因素分析[J]. 预防医学, 2025, 37(4): 382-385,389.
XIN Yulu, LI Mujia, DING Xiaohui, LU Yang, LI Wenjing, WANG Linping, LU Xiaoting, SONG Jing. Influencing factors for cognitive function among aluminum workers based on a quantile regression model. Preventive Medicine, 2025, 37(4): 382-385,389.
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