摘要目的 了解孕晚期孕妇与新生儿血清25（OH） D 水平。方法 选取2016年在丽水市妇幼保健院分娩的单胎孕妇及其新生儿各600人为研究对象，通过问卷调查收集基本信息，检测孕妇分娩前静脉血及新生儿脐血25（OH） D 水平。结果 孕妇分娩前 25（OH） D 平均水平为（36.25±14.92）nmol/L，其中451人维生素D 缺乏，占75.16%；新生儿25（OH） D平均水平为（29.59±16.13）nmol/L，其中495人维生素D 缺乏，占82.50%。孕妇分娩前25（OH） D 水平和新生儿25（OH） D 水平呈正相关（r=0.892，P<0.05）。孕期常规剂量补充维生素D（400 IU/d）的孕妇25（OH） D 水平高于未补充者（P<0.05）；孕妇血清25（OH） D 水平受季节的影响，夏季最高，冬季最低（P<0.05）。不同居住地、文化程度、孕期阳光暴露时间的孕妇25（OH） D 水平差异均无统计学意义（P>0.05）。结论 孕妇维生素D 水平偏低，且有季节性差异；孕妇维生素D 水平对新生儿维生素D水平有直接影响。
Abstract：Objective To explore the influencing factors and relationship of serum 25（OH） D levels between late-term pregnant women and newborns. Methods A total of 600 pregnant women and 600 newborns were selected in Lishui Maternal and Children Health Institution during 2016 and information were collected by questionnaires. Serum 25（OH）D levels in pregnant women's venous bloods and newborns' cord bloods were tested respectively before and after delivery. Results Serum 25（OH）D levels in 600 pregnant women's venous bloods before delivery were （36.25±14.92）nmol/L and 75.16%（451 pregnant women）had lower serum 25（OH）D levels. Serum 25（OH）D levels in newborns' cord bloods after delivery were（29.59±16.13）nmol/L and 82.50%（495 newborns）had lower serum 25（OH）D levels. The relationship of serum 25（OH）D levels between pregnant women and newborns was significant（r=0.892，P<0.05）. Vitamin D supplementation during pregnancy in pregnant women（400 IU/d）25（OH）D level was higher than those of not（P<0.05）. Serum 25（OH）D levels of pregnant women were influenced by seasons（P<0.05）as higher in summer and autumn and lower in spring and winter. Conclusion Serum 25（OH）D levels of pregnant women and newborns in Lishui were lower and different among seasons. Serum 25（OH）D levels of pregnant women could have influence on serum 25（OH）D levels of newborns. It should be encouraged to increase vitamin D intakes and outdoor activities，especially in spring and winter.
翁梅芬,靳春雷,蓝陈福. 孕晚期孕妇与新生儿维生素D水平分析[J]. 预防医学, 2017, 29(10): 991-993.
WENG Mei-fen，JIN Chun-lei，LAN Chen-fu. An analysis on the influencing factors and relationship of serum 25（OH）D levels between late-term pregnant women and newborns. Preventive Medicine, 2017, 29(10): 991-993.
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