Abstract：Objective To analyze influencing factors for comorbid chronic obstructive pulmonary disease (COPD) among elderly patients with pulmonary tuberculosis, so as to provide a basis for early screening and intervention of COPD among elderly patients with pulmonary tuberculosis. Methods Elderly patients with pulmonary tuberculosis hospitalized in Anhui Chest Hospital from July 1, 2022 to June 30, 2024 were selected as the study participants. Data on gender, age, smoking, alcohol consumption, type of pulmonary tuberculosis treatment, pulmonary cavity and drug resistant tuberculosis were collected through the electronic medical record system of Anhui Chest Hospital, and COPD was diagnosed according to the Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (2021 Revision). A multivariable logistic regression model was used to analyze the influencing factors for comorbid COPD among elderly patients with pulmonary tuberculosis. Results A total of 180 elderly patients with pulmonary tuberculosis were included, including 142 males (78.89%) and 38 females (21.11%). The median age was 70.00 (interquartile range, 10.00) years. There were 93 smoking cases, accounting for 51.67%, 47 alcohol consumption cases, accounting for 26.11%, 44 cases presented with pulmonary cavities, accounting for 24.44%, 110 cases had drug resistant tuberculosis, accounting for 61.11%. There were 53 cases comorbid with COPD, accounting for 29.44%; 127 cases comorbid without COPD, accounting for 70.56%. There were statistically significant differences in gender, smoking, type of pulmonary tuberculosis treatment, pulmonary cavity and drug resistant tuberculosis between the comorbid COPD group and the comorbid without COPD group (all P<0.05). Multivariable logistic regression analysis showed that smoking (OR=8.953, 95%CI: 3.322-24.155), pulmonary cavity (OR=11.832, 95%CI: 4.186-33.401) and drug resistant tuberculosis (OR=7.487, 95%CI: 2.222-25.280) were associated with a higher risk of comorbid COPD. Conclusion The proportion of comorbid COPD among elderly patients with pulmonary tuberculosis was relatively high, and smoking, pulmonary cavity and drug resistant tuberculosis were the influencing factors for comorbid COPD among elderly patients with pulmonary tuberculosis.
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