Social frailty and its influencing factors among elderly lung cancer patients undergoing chemotherapy
WANG Qingqing1, LIU Hong1, ZHANG Wei1, WANG Hongcai2, LI Xuhong1, WANG Yinuo1, ZHANG Yuanyuan1
1. School of Nursing, Shandong Second Medical University, Weifang, Shandong 261053, China; 2. Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong 261031, China
Abstract：Objective To investigate the current status and influencing factors of social frailty among elderly lung cancer patients undergoing chemotherapy, so as to provide evidence for developing early-screening and hierarchical-management strategies for social frailty. Methods From November 2025 to April 2026, hospitalized elderly lung cancer patients undergoing chemotherapy in the Department of Respiratory Medicine and Department of Oncology of a tertiary A hospital in Weifang City, Shandong Province were selected as study participants using convenience sampling method. Data on demographic characteristics, life behaviors, pathological staging, and number of chemotherapy cycles were collected through questionnaire surveys. Comorbidity burden, physical frailty, instrumental activities of daily living capacity, depressive symptoms, and social frailty were assessed using the Charlson Comorbidity Index, Clinical Frailty Scale, Instrumental Activities of Daily Living Scale, Patient Health Questionnaire-9, and Chinese Social Frailty Index Scale, respectively. A multivariable logistic regression model was used to analyze the influencing factors of social frailty among elderly lung cancer patients undergoing chemotherapy. Results A total of 249 elderly lung cancer patients undergoing chemotherapy were surveyed, including 192 males (77.11%) and 57 females (22.89%). The mean age of the participants was (68.86±5.83) years. Social frailty was identified in 73 participants, with a detection rate of 29.32%. Multivariable logistic regression analysis showed that junior high school education level or above (OR=0.171, 95%CI: 0.031-0.940), having a spouse (OR=0.132, 95%CI: 0.028-0.634), and higher scores of instrumental activities of daily living capacity (OR=0.360, 95%CI: 0.180-0.721) had a lower risk of social frailty; number of chemotherapy cycles ≥4 (OR=4.168, 95%CI: 1.131-15.361), higher Charlson Comorbidity Index (OR=4.749, 95%CI: 2.117-10.653), higher physical frailty scores (OR=3.274, 95%CI: 1.330-8.057), and higher depressive symptom scores (OR=2.005, 95%CI: 1.358-2.961) had a higher risk of social frailty. Conclusions The detection rate of social frailty among elderly lung cancer patients undergoing chemotherapy was relatively high. Education level, marital status, number of chemotherapy cycles, comorbidity burden, physical frailty, instrumental activities of daily living capacity and depressive symptoms were the influencing factors of social frailty among elderly patients with lung cancer undergoing chemotherapy.
王晴晴, 刘泓, 张伟, 王红彩, 李旭鸿, 王一诺, 张媛媛. 老年肺癌化疗患者社会衰弱及影响因素分析[J]. 预防医学, 2026, 38(9): 917-922.
WANG Qingqing, LIU Hong, ZHANG Wei, WANG Hongcai, LI Xuhong, WANG Yinuo, ZHANG Yuanyuan. Social frailty and its influencing factors among elderly lung cancer patients undergoing chemotherapy. Preventive Medicine, 2026, 38(9): 917-922.
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