Abstract:Objective To explore the effect of differentfamily tobacco controlpatterns on cotinine level and acute respiratory infections amonginfants.Methods A total of 300 infants were included, and were divided into 3 groups based on the tobacco control patterns: strictlytobacco-controlled group(97 cases), partlytobacco-controlledgroup(88 cases) and tobacco-uncontrolled group(115 cases).Urinary cotinine was measured in all participants. All participants were prospectively followed-up for 1 year, and the incidence of acute respiratory infections was recorded during the follow-up. Results The cotinine level of strictly tobacco-controlled group [0.45±0.21(μg/L)] was significantly lower than the other two groups[1.01±0.49(μg/L), 1.16±0.48(μg/L),P<0.05], and no significant differences were detected between the partly tobacco-controlled group and tobacco-uncontrolled group. The incidence of lower respiratory tract infection, not the upper respiratory tract infections, was significant different among the 3 groups (strictlytobacco-controlled group: 18.75%; partlytobacco-controlledgroup: 32.18%; tobacco-uncontrolled group: 37.72%)(P<0.05). The number of upper respiratory tract infections and lower respiratory tract infections was significantly different among the three groups. The difference was significant between strictly tobacco-controlled group and partly tobacco-controlled groupand between strictly tobacco-controlled group and tobacco-uncontrolled group (P<0.05). Conclusion Strict tobaccocontrol could reduce the prevalence of passive smoking and the incidence of respiratory infections amonginfants.
林楚君, 徐武秀, 徐武敏, 张凤飞. 不同家庭控烟方式对婴幼儿可替宁水平和急性呼吸道感染的影响[J]. 预防医学, 2016, 28(9): 896-898,902.
LIN Chu-jun, XU Wu-xiu, XU Wu-min, ZHANG Feng-fei. A study on the effect of different family tobacco control patterns on cotinine level and acute respiratory infections among infants. Preventive Medicine, 2016, 28(9): 896-898,902.
[1]WILLIAMS B G, GOUWS E, BOSCHI-PINTO C, et al.Estimates of world-wide distribution of child deaths from acute respiratory infections[J].Lancet Infect Dis, 2002, 2(1): 25-32. [2]陈珺芳,马海燕,汤静,等.杭州市归因于吸烟的疾病负担研究[J].浙江预防医学,2016,28(3):226-229,239. [3]姜垣,李强,肖琳,等.中国烟草流行与控制[J].中华流行病学杂志,2011,32(12):1181-1187. [4]杨功焕,马杰民,刘娜,等.中国人群2002年吸烟和被动吸烟的现状调查[J].中华流行病学杂志,2005,26(2):77-83. [5]刘明,苗菁.重庆市居民家庭及工作单位控烟现状研究[J].中国卫生事业管理,2014,31(2):150-152. [6]滕卫林,朱心强,王姝婷,等.杭州市区公共场所尼古丁暴露水平的研究[J].浙江预防医学,2012,24(9):1-3,9. [7]曹蓉,蔡秋茂,许燕君,等.广东省居民现在吸烟行为与家族环境因素关系的研究[J].中华流行病学杂志,2014,35(5):479-483. [8]王俊,宋瑞金.人体内可替宁检测技术研究进展[J]. 环境与健康杂志,2008,25(12):1111-1114. [9]何怡,徐东群.尿液和头发及唾液中尼古丁及其代谢物可替宁的气相色谱-质谱同时测定法[J].环境与健康杂志,2011,28(2):150-153. [10]胡亚美,江载芳.诸福棠实用儿科学[M].7版.北京:人民卫生出版社,2002:1167-1216. [11]PROTANO C, ANDREOLI R, MANINI P,et al. A tobacco-related carcinogen: assessing the impact of smoking behaviours of cohabitans on benzene exposure in children[J]. Tob Control,2012,21(3): 325-329. [12]关艳华,赵明耀,赵国强.反复上呼吸道感染患儿危险因素分析[J].中华医院感染学杂志,2014,24(2):480-482. [13]康旭丽.儿童反复上呼吸道感染危险因素分析[J].首都医药,2009,16(16):36-37. [14]刘汝青,宋宏,傅洪军,等.儿童被动吸烟现状及宣传教育效果评价[J].中国公共卫生,2007,23(1):121-122. [15]KRZYWIECKA M, OBUCHOWICZ A, BUKOWSKA C, et al. Evaluation of infants and younger children passive smoking at home and prevalence of their lower respiratory tract infectious[J]. Przegl Lek,2006,63(10): 827-830.