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预防医学  2016, Vol. 28 Issue (9): 879-882    
  论著 本期目录 | 过刊浏览 | 高级检索 |
丽水市2型糖尿病患者维生素D水平及相关因素分析
刘晓红, 曾长佑, 胡志勇, 陈晓蕾
丽水市疾病预防控制中心,浙江丽水323000
An analysis on the relationship between vitamin D levels and related factors among type 2 diabetic patients in Lishui City
LIU Xiao-hong, ZENG Chang-you, HU Zhi-yong, Chen Xiao-lei
The Center for Disease Control and Prevention of Lishni City,Zhejiang,Lishui,323000
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摘要 目的 分析2型糖尿病(T2DM)患者维生素D水平及相关影响因素,为干预性研究提供依据。方法 采用分层随机抽样方法抽取丽水市10个街道/乡镇270例T2DM患者,开展问卷调查、体格检查及实验室检测。采用高效液相色谱-串联质谱法检测血清25(OH)D3水平,并分析其相关影响因素。结果 270例T2DM患者血清25(OH)D3平均为(22.97±8.07)ng/mL;男性患者25(OH)D3中位数为25 ng/mL,高于女性患者的21 ng/mL(P<0.05);农村患者为23 ng/mL,高于城市患者的20 ng/mL(P<0.05);超重及肥胖的T2DM患者低于BMI正常者(P<0.05)。多元线性回归分析显示,性别、城乡户籍和户外活动时间是维生素D水平的影响因素, β值分别为-5.178、2.369和2.026(P均<0.05)。结论 T2DM患者维生素D水平与性别、城乡户籍、户外活动时间相关,应加强对T2DM患者的维生素D水平监测与户外活动干预。
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刘晓红
曾长佑
胡志勇
陈晓蕾
关键词 2型糖尿病维生素D相关因素    
AbstractObjective To analyze serum vitamin D level in patients with type 2 diabetes mellitus(T2DM),and to provide evidence for the intervention. Methods A total of 270 blood samples from patients with T2DM by multi-stage random sampling in 10 streets/towns in Lishui City were collected to test 25-hydroxyvitamin D level by high performance liquid chromatography- tandem mass spectrometry. Results The average level of 270 case of T2DM patients' 25-hydroxyvitamin D was (22.97±8.07) ng/mL. Gender, household registration, BMI stage and 25-hydroxyvitamin D level were statistically significant, respectively (Z=4.13, P<0.05), (Z=2.44, P<0.05), (F=3.21,P<0.05). By multiple linear regression analysis, we found that gender, household registration and length of outdoor exercise time was related to vitamin D level, the B value were-5.178, 2.369, and 2.026, respectively(P<0.05). Conclusion T2DM patients had lower level vitamin D in their blood. Vitamin D had negative correlation with gender, household registration, and outdoor exercise time. T2DM patients’ vitamin D monitoring and outdoor activities should be strengthened.
Key wordsType 2 diabetes mellitus    Vitamin D    Related factors
收稿日期: 2016-03-07          
中图分类号:  R587.1  
基金资助:国家自然科学基金项目(81372981);浙江丽水市科技计划项目(2014JYZB61)
通信作者: 刘晓红,E-mail:67573853@qq.com   
作者简介: 刘晓红,硕士在读,主管医师,主要从事慢性病防制工作
引用本文:   
刘晓红, 曾长佑, 胡志勇, 陈晓蕾. 丽水市2型糖尿病患者维生素D水平及相关因素分析[J]. 预防医学, 2016, 28(9): 879-882.
LIU Xiao-hong, ZENG Chang-you, HU Zhi-yong, Chen Xiao-lei. An analysis on the relationship between vitamin D levels and related factors among type 2 diabetic patients in Lishui City. Preventive Medicine, 2016, 28(9): 879-882.
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http://www.zjyfyxzz.com/CN/      或      http://www.zjyfyxzz.com/CN/Y2016/V28/I9/879
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