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预防医学  2025, Vol. 37 Issue (8): 789-793,798    DOI: 10.19485/j.cnki.issn2096-5087.2025.08.007
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猴痘病原学和流行病学研究进展
刘珊, 张劲松, 张文利, 王贺, 朱文烨 综述, 沙琨 审校
海军军医大学卫生勤务学系,上海 200433
Research progress on the etiology and epidemiology of monkeypox
LIU Shan, ZHANG Jingsong, ZHANG Wenli, WANG He, ZHU Wenye, SHA Kun
Faculty of Military Health Service, Naval Medical University, Shanghai 200433, China
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摘要 猴痘是由猴痘病毒感染引起的一种既往局限于非洲流行的人畜共患传染病。自2022年起猴痘迅速在全球范围广泛传播,波及全球130个国家和地区,世界卫生组织分别于2022年和2024年宣布其为国际关注的突发公共卫生事件。猴痘病毒变异速度加快,流行毒株呈多样化,儿童、男男性行为人群为主要高危人群,无症状感染及非典型轻度皮疹等增加鉴别诊断难度,对猴痘的诊疗和防控提出挑战。本文检索1958年1月—2025年1月有关猴痘的文献,对猴痘的病原学特征、流行特征、临床特征和防治策略等方面进行综述,为预防和治疗猴痘提供依据。
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刘珊
张劲松
张文利
王贺
朱文烨
沙琨
关键词 猴痘猴痘病毒流行特征治疗预防    
Abstract:Monkeypox is a zoonotic disease caused by the monkeypox virus, which was previously limited to epidemics in Africa. Since 2022, monkeypox has rapidly spread worldwide, affecting 130 countries and regions. The World Health Organization declared it a public health emergency of international concern, in 2022 and 2024, respectively. The monkeypox virus has exhibited accelerated mutation rates, with diverse circulating strains. Children and men who have sex with men have emerged as the primary high-risk group. Additionally, the increase in asymptomatic infections and atypical mild rashes has complicated differential diagnosis, posing entirely challenges to the diagnosis, treatment, and prevention and control of monkeypox. This article reviews the research progress on the etiological characteristics, epidemiological features, clinical manifestations, and prevention and treatment strategies of monkeypox by retrieving the literature on monkeypox from January 1958 to January 2025, so as to provide the basis for the prevention and treatment of monkeypox.
Key wordsmonkeypox    monkeypox virus    epidemiological characteristics    treatment    prevention
收稿日期: 2025-03-21      修回日期: 2025-07-28      出版日期: 2025-08-10
中图分类号:  R511  
基金资助:国家自然科学基金项目(12131020); 上海市教育委员会人工智能专项(2024RGYB004)
作者简介: 刘珊,硕士,主要从事生物信息学、数据挖掘研究工作
通信作者: 沙琨,E-mail:kunie@smmu.edu.cn   
引用本文:   
刘珊, 张劲松, 张文利, 王贺, 朱文烨, 沙琨. 猴痘病原学和流行病学研究进展[J]. 预防医学, 2025, 37(8): 789-793,798.
LIU Shan, ZHANG Jingsong, ZHANG Wenli, WANG He, ZHU Wenye, SHA Kun. Research progress on the etiology and epidemiology of monkeypox. Preventive Medicine, 2025, 37(8): 789-793,798.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2025.08.007      或      http://www.zjyfyxzz.com/CN/Y2025/V37/I8/789
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