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预防医学  2017, Vol. 29 Issue (3): 221-225    DOI: 10.19485/j.cnki.issn1007-0931.2017.03.002
  论著 本期目录 | 过刊浏览 | 高级检索 |
碳酸饮料与骨丢失关系的Meta分析
邹艳,李丹,孟佳,黄李春,方跃强,章荣华
浙江省疾病预防控制中心,浙江杭州 310051
An assessment of the relationship betweenbone loss and carbonated beverages: a meta-analysis
ZOU Yan,LI Dan,MENG Jia, HUANG Li-chun,FANG Yue-qiang,ZHANG Rong-hua
The Center for Disease Control and Prevention of Zhejiang Province,Hangzhou,Zhejiang,310051,China
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摘要 目的 综合评价碳酸饮料对骨丢失的影响。方法 系统检索PubMed、Cochrane Library、EBSCO、中国高等教育文献保障系统(CALIS)和中国知网(CNKI)数据库中1980—2015年发表的研究碳酸饮料和骨丢失关系的文献。采用Stata 11.0软件进行Meta分析。结果 共纳入符合标准的文献10篇,其中4篇报道了饮用碳酸饮料与低骨密度的关系,4篇报道了饮用碳酸饮料与骨折的关系,3篇报道了饮用可乐与低骨密度的关系,4篇报道了饮用可乐与骨折的关系。Meta分析结果显示,饮用碳酸饮料可能是导致低骨密度(OR=1.28,95%CI:1.02~1.60)和骨折(OR=1.53,95%CI:1.04~2.26)的危险因素,饮用可乐可能是导致骨折的危险因素(OR=2.00,95%CI:1.24~3.24)。结论 饮用碳酸饮料可能导致骨丢失。
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邹艳
李丹
孟佳
黄李春
方跃强
章荣华
关键词 碳酸饮料 骨密度 骨折Meta分析    
AbstractObjective The aim of the present study was to estimate the quantitative contributions of carbonated beverages consumption to bone loss.Methods We performed computer searches of PubMed,Cochrane Library,EBSCO,CALIS to search for studies investigating the relationship between carbonated beverages and bone loss.For carbonated beverages investigated in a comparative way,we use random effect model to compute pooled odds ratios (ORs) and Cochran Q statistic to estimate the heterogeneity.Results A total of 10 studies met the inclusion criteria and the relationships between carbonated beverages and bone loss were considered,including colas and bone loss.The following associations were found for carbonated beverages and low bone density (OR=1.28,95%CI=1.02-1.60),carbonated beverages and bone fractures (OR=1.53,95%CI=1.04-2.26),colas and bone fractures (OR=2.00,95%CI=1.24-3.24).Conclusion The present results indicate that carbonated beverages were associated with bone loss.This meta-analysis may have important public health implications given the widespread use of carbonated beverages.
Key wordsCarbonated beverages    Bone density    Fracture;Meta-analysis
          出版日期: 2017-03-15
中图分类号:  R683  
作者简介: 邹艳,硕士,副主任医师,主要从事流行病学研究工作
通信作者: 章荣华,E- mail: rhzhang@cdc.zj.cn   
引用本文:   
邹艳, 李丹, 孟佳, 黄李春, 方跃强, 章荣华. 碳酸饮料与骨丢失关系的Meta分析[J]. 预防医学, 2017, 29(3): 221-225.
ZOU Yan, LI Dan, MENG Jia, HUANG Li-chun, FANG Yue-qiang, ZHANG Rong-hua. An assessment of the relationship betweenbone loss and carbonated beverages: a meta-analysis. Preventive Medicine, 2017, 29(3): 221-225.
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