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预防医学  2022, Vol. 34 Issue (5): 515-518,529    DOI: 10.19485/j.cnki.issn2096-5087.2022.05.019
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放射治疗患者医院感染的影响因素分析
孙菲菲, 楼晓红, 虞洪斌
义乌市中心医院医院感染管理科,浙江 义乌 322000
Influencing factors of nosocomial infections among radiotherapy patients
SUN Feifei, LOU Xiaohong, YU Hongbin
Department of Nosocomial Infection Management, Yiwu Central Hospital, Yiwu, Zhejiang 322000, China
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摘要 目的 了解放射治疗患者医院感染的影响因素,为防制放射治疗患者医院感染提供依据。方法 选择义乌市中心医院2019—2020年接受放射治疗的恶性肿瘤患者为调查对象。通过医院电子病历系统收集患者人口学信息、放射治疗和医院感染情况;采用多因素logistic回归模型分析放射治疗患者医院感染的影响因素。结果 纳入放射治疗患者553例,男性268例,占48.46%;年龄为(60.31±13.66)岁;住院时间为(28.67±14.32)d;放射治疗周期为(3.63±1.89)周。发生医院感染46例,感染率为8.32%。感染部位前三位是下呼吸道(14例占30.43%)、口腔(10例占21.74%)和泌尿道(8例占17.39%);分离出病原菌42株,以革兰阴性菌为主,25株占59.52%。多因素logistic回归分析结果显示,放射治疗周期≥4周(OR=3.857,95%CI:1.896~7.846)、有放射治疗暴露(OR=3.254,95%CI:1.561~6.783)、有动静脉置管(OR=2.165,95%CI:1.144~4.098)、有泌尿道插管(OR=6.028,95%CI:1.841~19.734)、营养状况较差(OR=3.933,95%CI:1.493~10.360)与放射治疗患者医院感染相关。结论 放射治疗周期、放射治疗暴露、动静脉置管、泌尿道插管和营养状况是放射治疗患者医院感染的影响因素。
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关键词 放射治疗肿瘤医院感染影响因素    
AbstractObjective To investigate the influencing factors of nosocomial infections among patients undergoing radiotherapy, so as to provide insights into nosocomial infection control among radiotherapy patients. Methods The malignant tumor patients receiving radiotherapy in Yiwu Central Hospital from 2019 to 2020 were selected. Their demographic features, radiotherapy and nosocomial infections were collected through the eletronic medical records. The factors affecting nosocomial infections were identified among radiotherapy patients using a multivariable logistic regression model. Results Totally 553 malignant tumor patients receiving radiotherapy were enrolled, including 268 men ( 48.46% ) and with a mean age of ( 60.31±13.66 ) years. The mean duration of hospital stay was ( 28.67±14.32 ) days, and the mean radiotherapy cycle was ( 3.63±1.89 ) weeks. A total of 46 patients were detected with nosocomial infections, with prevalence of 8.32%. The top three sites with the highest prevalence of nosocomial infections included the lower respiratory tract ( 14 cases, 30.43% ), oral cavity ( 10 cases, 21.74 ) and urinary tract ( 8 cases, 17.39% ), and 42 bacterial strains were isolated, with Gram-negative bacteria as the predominant strains ( 25 strains, 59.52% ). Multivariable logistic regression analysis showed that radiotherapy cycle of 4 weeks and longer ( OR=3.857, 95%CI: 1.896-7.846 ), radiotherapy exposure ( OR=3.254, 95%CI: 1.561-6.783 ), arteriovenous catheterization ( OR=2.165, 95%CI: 1.144-4.098 ), urinary tract intubation ( OR=6.028, 95%CI: 1.841-19.734 ) and poor nutritional status ( OR=3.933, 95%CI: 1.493-10.360 ) were associated with nosocomial infections among radiotherapy patients. Conclusion Radiotherapy cycle, exposure to radiotherapy, arteriovenous catheterization, urinary tract intubation and poor nutritional status are factors affecting nosocomial infections among radiotherapy patients.
Key wordsradiotherapy    tumor    nosocomial infection    influencing factor
收稿日期: 2022-01-25      修回日期: 2022-03-07     
中图分类号:  R730.55  
  R63  
通信作者: 虞洪斌,E-mail:hongbinyu85@163.com   
作者简介: 孙菲菲,硕士,医师,主要从事医院感染管理工作
引用本文:   
孙菲菲, 楼晓红, 虞洪斌. 放射治疗患者医院感染的影响因素分析[J]. 预防医学, 2022, 34(5): 515-518,529.
SUN Feifei, LOU Xiaohong, YU Hongbin. Influencing factors of nosocomial infections among radiotherapy patients. Preventive Medicine, 2022, 34(5): 515-518,529.
链接本文:  
http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2022.05.019      或      http://www.zjyfyxzz.com/CN/Y2022/V34/I5/515
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