Abstract:Objective To analyze the survival rate and its influencing factors of HIV/AIDS patients after antiviral therapy in Yinzhou District of Ningbo,so as to provide basis for AIDS prevention and control. Methods The data of HIV/AIDS patients who received highly active antiretroviral therapy(HAART)in Yinzhou District from May 2005 to December 2014 were retrieved from the national AIDS comprehensive prevention and control information system;the survival rate was calculated by life table and Kaplan-Meier analysis;the influencing factors for survival time was analyzed by a multivariate cox proportional risk regression model. Results Among 327 HIV/AIDS patients,twenty four were dead and three were lost. The average follow-up time was(5.63 ± 1.98)years. The cumulative survival rates of the subjects were 95%,92%,and 90% at 1,5,and 10 years after HAART. The Results of multivariate cox proportional risk regression analysis showed that patients who were at younger age when treatment begins(HR=1.053,95%CI: 1.001-1.108),were transmitted by homosexual contact(HR=0.026,95%CI: 0.003-0.253)and by blood transmission(HR=0.043,95%CI: 0.006-0.309),had high level of CD4+T lymphocyte at baseline(HR=0.993,95%CI: 0.988-0.998),and had viral load below the detection limit after six months of treatment(HR=0.028,95%CI: 0.009-0.084)were less likely to be dead. Conclusions The survival rate of HIV/AIDS patients after HAART is high,and is associated with the age when treatment begins,route of transmission,baseline CD4+T lymphocyte level and viral load after six months of treatment.
王斌, 龚德光, 朱洁群. 鄞州区艾滋病抗病毒治疗患者生存率及影响因素分析[J]. 预防医学, 2020, 32(4): 346-350.
WANG Bin, GONG Deguang, ZHU Jiequn. Survival rate and influencing factors of HIV/AIDS after highly active antiretroviral therapy in Yinzhou District. Preventive Medicine, 2020, 32(4): 346-350.
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