Factors affecting blood lipid control among residents at a high risk of atherosclerotic cardiovascular disease
HUANG Wen1, HE Liang2, FU Lingjuan3, WENG Lixia4, ZHANG Xinxi5, ZHU Shuxia6, ZHANG Yanghui7, CHEN Qifeng1
1. Department of Non-communicable Chronic Diseases Control and Prevention, Shaoxing Center for Disease Control and Prevention, Shaoxing, Zhejiang 312000, China; 2. Zhuji Center for Disease Control and Prevention, Zhuji, Zhejiang 311800, China; 3. Keqiao District Center for Disease Control and Prevention, Shaoxing, Zhejiang 312030, China; 4. Shengzhou Center for Disease Control and Prevention, Shengzhou, Zhejiang 312400, China; 5. Shangyu District Center for Disease Control and Prevention, Shaoxing, Zhejiang 312300, China; 6. Yuecheng District Center for Disease Control and Prevention, Shaoxing, Zhejiang 312000, China; 7. Xinchang County Center for Disease Control and Prevention, Xinchang, Zhejiang 312500, China
Abstract：Objective To investigate the proportion of achieving the blood lipid control target and its influencing factors among residents at a high risk of atherosclerotic cardiovascular disease (ASCVD), so as to provide insights into management of blood lipid among residents at a high risk of ASCVD. Methods Residents at a high risk of ASCVD and at ages of 35 to 70 years were sampled using a multi-stage cluster sampling method from 6 counties (districts) in Shaoxing City from May to July 2021. The residents' demographics, smoking, alcohol consumption and medical history of chronic diseases were collected using questionnaires, the height, weight, waist circumference (WC) and blood pressure were measured, and the total cholesterol (TC), triacylglycerol (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and fasting blood glucose were detected. The proportion of blood lipids achieving the control target was analyzed, and factors affecting the proportion of blood lipids achieving the control target were identified using a multivariable logistic regression model. Results A total of 1 695 individuals at a high risk of ASCVD were enrolled, including 940 men (55.46%) and 755 women (44.54%), with a mean age of (62.56±6.08) years. There were 285 participants that achieved the target of blood lipid control (16.81%). Multivariable logistic regression analysis identified gender (male, OR=1.962, 95%CI: 1.396-2.758), age (OR=1.037, 95%CI: 1.013-1.061), WC (OR=0.979, 95%CI: 0.964-0.995), diastolic blood pressure (OR=0.981, 95%CI: 0.967-0.994), smoking (OR=1.485, 95%CI: 1.034-2.133), alcohol consumption (OR=0.684, 95%CI: 0.498-0.941), hypertension (OR=1.428, 95%CI: 1.006-2.207), administration of hypoglycemic drugs (OR=2.326, 95%CI: 1.720-3.144) as factors affecting the achievement of the target for blood lipid control among residents at a high risk of ASCVD. Conclusion Individuals at a high risk of ASCVD with higher WC, higher diastolic blood pressure and alcohol consumption are less likely to achieve the target for blood lipid control, while male individuals with older age, hypertension and administration of hypogcemic drugs are more likely to achieve the target for blood lipid control.
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