武汉市放射工作人员甲状腺功能的影响因素分析

doi:10.19485/j.cnki.issn2096-5087.2023.05.009

预防医学

2023, Vol. 35

Issue (5): 406-409 DOI: 10.19485/j.cnki.issn2096-5087.2023.05.009

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武汉市放射工作人员甲状腺功能的影响因素分析

戴霞云¹, 罗永斌², 刘安生², 王帆², 陈振龙², 齐素芹²

1.武汉市职业病防治院科教科,湖北武汉 430015;
2.武汉市职业病防治院,湖北武汉 430015

Influencing factors for thyroid function among radiation workers in Wuhan City

DAI Xiayun¹, LUO Yongbin², LIU Ansheng², WANG Fan², CHEN Zhenlong², QI Suqin²

1. Department of Science and Education, Wuhan Prevention and Treatment Center for Occupational Diseases, Wuhan, Hubei 430015, China;
2. Wuhan Prevention and Treatment Center for Occupational Diseases, Wuhan, Hubei 430015, China

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摘要目的了解武汉市放射工作人员甲状腺功能水平及其影响因素,为放射工作人员职业健康监护提供依据。方法选择2022年1—10月在武汉市职业病防治院健康体检的放射工作人员为调查对象,收集性别、年龄、吸烟、饮酒、疾病史、用药史、职业照射种类和工龄。采用磁微粒化学发光法检测三碘甲状腺原氨酸（TT3）、甲状腺素（TT4）、游离甲状腺素（FT4）、游离三碘甲状腺原氨酸（FT3）和促甲状腺激素（TSH）;采用热释光剂量测定法监测个人剂量当量,计算年累积剂量;采用多因素logistic回归模型分析甲状腺功能的影响因素。结果调查978人,年龄M（Q_R）为32.00（10.00）岁;男性782人,占79.96%;女性196人,占20.04%。吸烟246人,占25.15%。饮酒257人,占26.28%。有放射工作史489人,占50.00%。年累积剂量M（Q_R）为0.20（0.24）mSv。检出甲状腺功能异常72例,异常率为14.72%。多因素logistic回归分析结果显示,女性（OR=1.925,95%CI：1.061~3.490）、有放射工作史（OR=2.810,95%CI：1.119~7.057）和从事医学应用（OR=1.915,95%CI：1.101~3.332）与甲状腺功能异常有统计学关联。结论武汉市放射工作人员甲状腺功能异常率为14.72%,电离辐射接触史、职业照射种类和性别是主要影响因素。

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	戴霞云
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关键词 ：放射工作人员, 电离辐射, 甲状腺功能

Abstract：Objective To investigate the thyroid functions and influencing factors among radiation workers in Wuhan City, so as to provide insights into occupational health monitoring among radiation workers. Methods Radiation workers receiving physical examinations in Wuhan Prevention and Treatment Center for Occupational Diseases from January to October 2022 were enrolled, and participants' gender, age, smoking, alcohol consumption, medical history, medication use, types of occupational radiation and work duration were collected. Triiodothyronine (TT3), thyroxine (TT4), free thyroxine (FT4), free triiodothyronine (FT3) and thyroid stimulating hormone (TSH) were measured using a magnetic microparticle-based chemiluminescence immunoassay. Personnel dose equivalent was monitored using thermoluminescent dosimetry, and annual cumulative radiation dose was estimated. Factors affecting thyroid function were identified using a multivariable linear regression model. Results Totally 978 radiation workers were recruited, with a median age of 32.00 (interquartile range, 10.00) years, and including 782 men (79.96%) and 196 women (20.04%). There were 246 smokers (25.15%), 257 workers with alcohol consumption (26.28%) and 489 with a history of radiation work (50.00%). The median annual cumulative radiation dose was 0.20 (interquartile range, 0.24) mSv. The percentage of abnormal thyroid function was 14.72%. Multivariable logistic regression analysis showed that women (OR=1.925, 95%CI: 1.061-3.490), history of radiation work (OR=2.810, 95%CI: 1.119-7.057) and involving in medical application (OR=1.915, 95%CI: 1.101-3.332) were associated with abnormal thyroid function. Conclusions The percentage of abnormal thyroid function was 14.72% among radiation workers in Wuhan City. History of exposure to ionizing radiation, types of occupational radiation and gender were main factors affecting thyroid function.

Key words： radiation worker ionizing radiation thyroid function

收稿日期: 2023-01-13 修回日期: 2023-04-07 出版日期: 2023-05-10

中图分类号:

R581

基金资助:武汉市卫生健康科研基金资助项目（WG21Q01,WG19Y04）; 武汉科技大学职业危害识别与控制湖北省重点实验室（OHIC2022Z10）

通信作者: 齐素芹,E-mail：958032166@qq.com

作者简介: 戴霞云,博士,主管医师,主要从事环境流行病学工作

引用本文:

戴霞云, 罗永斌, 刘安生, 王帆, 陈振龙, 齐素芹. 武汉市放射工作人员甲状腺功能的影响因素分析[J]. 预防医学, 2023, 35(5): 406-409.
DAI Xiayun, LUO Yongbin, LIU Ansheng, WANG Fan, CHEN Zhenlong, QI Suqin. Influencing factors for thyroid function among radiation workers in Wuhan City. Preventive Medicine, 2023, 35(5): 406-409.

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