Factors affecting dyslipidemia among adult residents in Hefei City
SUN Feng1,2, ZHANG Lei2, WANG Qian2, YUAN Lei1, LIU Sijun1
1. School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China; 2. Hefei Center for Disease Prevention and Control, Hefei, Anhui 230061, China
Abstract：Objective To investigate the prevalence and influencing factors of dyslipidemia among adult residents in Hefei City, so as to provide the evidence for formulating the dyslipidemia control strategy. Methods A total of 10 812 permanent residents at ages of 18 years were randomly sampled from 5 counties (districts) in Hefei City using a multi-stage stratified cluster random sampling method. Participants' demographic features, dietary behaviors and development of chronic diseases were collected using questionnaire surveys, and the height, body weight, waist circumference and blood lipids were measured. The prevalence of dyslipidemia was analyzed, and the factors affecting the development of dyslipidemia were identified using a multivariable logistic regression model. Results Totally 10 812 valid questionnaires were recovered, with an effective recovery rate of 92.02%. The participants had a male to female ratio of 0.85∶1, a mean age of (51.89±12.56) years. The prevalence of dyslipidemia was 25.20%, and hypertriglyceridemia and low high-density lipoprotein cholesterol (HDL-C) were predominant types of dyslipidemia, with prevalence of 12.70% and 10.20%, respectively. Multivariable logistic regression analysis showed that urban areas (OR=1.340, 95%CI: 1.219-1.474), age of 40 years and older (40 to 59 years, OR=1.181, 95%CI: 1.047-1.333; 60 to 88 years, OR=1.321, 95%CI: 1.154-1.513), alcohol consumption (OR=1.205, 95%CI: 1.093-1.329), insufficient physical activity (OR=1.217, 95%CI: 1.111-1.332), static behavior duration of 3 h/d and longer (OR=1.126, 95%CI: 1.027-1.234), overweight (OR=1.162, 95%CI: 1.045-1.291), obesity (OR=1.310, 95%CI: 1.097-1.564), central pre-obesity (OR=1.236, 95%CI: 1.102-1.387), central obesity (OR=1.414, 95%CI: 1.247-1.603), hypertension (OR=1.279, 95%CI: 1.107-1.477), diabetes (OR=2.192, 95%CI: 1.820-2.640), medical insurance (OR=0.594, 95%CI: 0.395-0.893) and self-rated “very good/good” oral health (OR=0.731, 95%CI: 0.576-0.927) were factors affecting the development of dyslipidemia. Conclusion The risk of dyslipidemia is high among adult residents living in urban areas, middle-aged and elderly residents, residents with alcohol consumption, insufficient physical activity, overweight, obesity, central pre-obesity, central obesity, hypertension and diabetes.
[1] GBD 2017 Risk Factor Collaborators.Global,regional,and national comparative risk assessment of 84 behavioural,environmenetal and occupational,and metabolic risks or clusters of risks for 195 countries and territories,1990-2017:a systematic analysis for the Global Burden of Disease Study 2017BD 2017 Risk Factor Collaborators.Global,regional,and national comparative risk assessment of 84 behavioural,environmenetal and occupational,and metabolic risks or clusters of risks for 195 countries and territories,1990-2017:a systematic analysis for the Global Burden of Disease Study 2017[J].Lancet,2018,392(10159):1923-1994. [2] 孟焕,邱琳,飒日娜,等.陕西省成人血脂异常流行现状及相关因素研究[J].中国慢性病预防与控制,2021,29(10):750-755. MENG H,QIU L,SA R N,et al.Prevalence and related factors of dyslipidemia among adults of Shaanxi Province[J].Chin J Prev Contr Chron Dis,2021,29(10):750-755. [3] 赵松华,陈桂华,李忻,等.贵州省5市(县)18岁及以上人群血脂异常流行特点[J].微量元素与健康研究,2018,35(3):51-53. ZHAO S H,CHEN G H,LI X,et al.Investigation of distribution characteristics of plasma lipids levels in people over 18 years old in 5 cities(counties)of Guizhou province[J]. Studies Trace Elem Health,2018,35(3):51-53. [4] 胡世云,俞蔚,徐小玲,等.浙江省35~75岁常住居民血脂异常情况调查[J].预防医学,2020,32(5):437-441. HU S Y,YU W,XU X L,et al.Prevalence of dyslipidemia among the residents aged 35-75 years in Zhejiang Province[J].Prev Med,2020,32(5):437-441. [5] ZHANG F,XING Y,WU Y,et al.The prevalence,awareness,treatment,and control of dyslipidemia in northeast China:a population-based cross-sectional survey[J/OL].Lipids Health Dis,2017,16(1)[2022-10-17].http://doi.org/10.1186/s12944-017-0453-2. [6] 徐伟,邢秀雅,贺琴,等.安徽省2015年成年人血脂异常流行现状及相关因素研究[J].中华流行病学杂志,2020,41(2):195-200. XU W,XING X Y,HE Q,et al.A cross-sectional study on the prevalence and related factors of dyslipidemia among adults in Anhui province,in 2015[J].Chin J Epidemiol,2020,41(2):195-200. [7] 中华人民共和国卫生和计划生育委员会.人群健康监测人体测量方法:WS/T 424—2013[S].北京:中国标准出版社,2013. National Health and Family Planning Commission of the People's Republic of China.Anthropometric measurements method in health surveillance:WS/T 424-2013[S].Beijing:Standards Press of China,2013. [8] 中国成人血脂异常防治指南修订联合委员会.中国成人血脂异常防治指南(2016年修订版)[J].中华全科医师杂志,2017,16(1):15-35. Joint Committee Issued Chinese Guideline for the Management of Dyslipidemia in Adults.2016 Chinese guideline for the managementof dyslipidemia in adults[J].Chin J Gen Pract,2017,16(1):15-35. [9] 中国疾病预防控制中心.中国慢性病及其危险因素监测报告2018[M].北京:人民卫生出版社,2021. Chinese Center for Disease Control and Prevention.Report on chronic disease risk factor survillance in China,2018[M].Beijing:People's Medical Publishing House,2021. [10] 辛蔚妮. 口腔健康影响程度量表(OHIP-14中文版)的验证及应用研究[D].广州:中山大学,2006. XIN W N.Validation and application of a Chinese version of the Oral Health Impact Profile-14(OHIP-14)[D].Guangzhou:Sun Yat-sen University,2006. [11] 中华人民共和国卫生和计划生育委员会.成人体重判定:WS/T 428—2013[S].北京:中国标准出版社,2013. National Health and Family Planning Commission of the People's Republic of China.Criteria of weight for adults:WS/T 428-2013[S].Beijing:Standards Press of China,2013. [12] 中国高血压防治指南修订委员会,高血压联盟(中国),中华医学会心血管病学分会,等.中国高血压防治指南(2018年修订版)[J].中国心血管杂志,2019,24(1):24-56. Writing Group of 2018 Chinese Guidelines for the Management of Hypertension,Chinese Hypertension League,Chinese Society of Cardiology,et al.2018 Chinese guidelines for the management of hypertension[J].Chin J Cardiovasc Med,2019,24(1):24-56. [13] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2020年版)(上)[J].中国实用内科杂志,2021,41(8):668-695. Chinese Diabetes Society.Guideline for the prevention and treatment of type 2 diabetes mellitus in China(2020 edition)(Part 1)[J].Chin J Pract Intern Med,2021,41(8):668-695. [14] 李辉,段东辉,王永,等.宁波市居民血脂异常及影响因素分析[J].预防医学,2019,31(5):474-477. LI H,DUAN D H,WANG Y,et al.Prevalence and influencing factors of dyslipidemia among Ningbo residents[J].Prev Med,2019,31(5):474-477. [15] 陶寄,盛敏阳,许云峰,等.海宁市居民血脂异常的影响因素分析[J].预防医学,2022,34(8):821-825. TAO J,SHENG M Y,XU Y F,et al.Factors affecting dyslipidemia among residents in Haining City[J].Prev Med,2022,34(8):821-825. [16] 胡彩红,张梅,李纯,等.我国成年居民饮酒行为与血脂异常关系研究[J].疾病监测,2020,35(8):697-705. HU C H,ZHANG M,LI C,et al.Relationship between drinking behavior and dyslipidemia in adults in China[J].Dis Survill,2020,35(8):697-705. [17] ZHANG M,DENG Q,WANG L,et al.Prevalence of dyslipidemia and achievement of low-density lipoprotein cholesterol targets in Chinese adults:a nationally representative survey of 163 641 adults[J].Int J Cardiol,2018,260:196-203. [18] 葛莹,颜维,何岱昆.上海市郊区某社区居民不同血压类型与血脂水平的相关性研究[J].中国初级卫生保健,2021,35(2):31-35. GE Y,YAN W,HE D K.Analysis on the correlation between different types of hypertension and lipid levels in population from a community in the suburb of Shanghai[J].Chin Prim Health Care ,2021,35(2):31-35. [19] 李佳,鄢华,苏晞.糖尿病血脂异常的药物治疗新进展[J].中国循证心血管医学杂志 ,2022,14(2):247-249. LI J,YAN H,SU X.New progress in medication of diabetic dyslipidemia[J].Chin J Evid Based Cardiovasc Med,2022,14(2):247-249. [20] 贺江珊,张莉,李春君,等.天津市成人夜间睡眠时长与血脂水平的关系[J].中华疾病控制杂志,2022,26(2):150-154. HE J S,ZHANG L,LI C J,et al.Associations of night sleep duration with blood lipid levels of adults in Tianji[J].Chin J Dis Control Prev,2022,26(2):150-154. [21] PEJCIĆ A,KESIĆ L,ILIĆ S,et al.Association between chronic periodontitis and serum lipid levels[J].Vojnosanit Pregl,2012,69(9):771-777. [22] 刘文静. 老年糖尿病人牙周健康状况及其与血脂、凝血指标相关性的研究[D].西安:第四军医大学,2015. LIU W J.Study on the correlation among the periondontal health and serum lipids,coagulation of elderly diabetics[D].Xi'an:Fourth Military Medical University,2015. [23] 朱艳,杨懿君,许哲.血脂水平与牙周炎发病相关性及牙周基础治疗对血脂的影响[J].中华口腔医学研究杂志(电子版),2020,14(3):176-180. ZHU Y,YANG Y J,XU Z.Correlation between serum lipid level and periodontitis and the influence of basic periodontal therapy on serum lipid[J].Chin J Stomatol Res(Electron Ed),2020,14(3):176-180.
