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预防医学  2018, Vol. 30 Issue (1): 5-8    DOI: 10.19485/j.cnki.issn2096-5087.2018.01.002
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台州市美沙酮维持治疗人群特征分析
叶小红1, 柏鸿凌2, 许圆圆3, 吴琼海3, 沈伟伟3, 丁盈盈2, 林海江3
1. 临海市疾病预防控制中心传防科,浙江 临海 317000;
2. 复旦大学公共卫生学院流行病学教研室;
3. 台州市疾病预防控制中心
Characteristics of patients on methadone maintenance treatment in Taizhou City
YE Xiao-hong*, BAI Hong-ling, XU Yuan-yuan, WU Qiong-hai, SHEN Wei-wei, DING Ying-ying, LIN Hai-jiang
*The Center for Disease Control and Prevention of Linhai City,Taizhou,Zhejiang 317000,China
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摘要 目的 了解台州市美沙酮维持治疗(MMT)患者的人口学特征及MMT维持率的影响因素。方法 从全国MMT数据管理系统导出2006—2014年台州市首次入组MMT的鸦片或海洛因成瘾者信息,对其人口学特征、既往毒品使用情况和MMT治疗情况进行描述性分析,采用Logistic回归模型分析MMT维持率的影响因素。结果 2006—2014年台州市首次入组MMT的鸦片或海洛因成瘾者共2 262例,其中男性1 980例(87.53%),女性282例(12.47%);未婚、离异或丧偶1 261例,占55.75%;初中及以下文化程度2 006例,占88.68%;初次吸毒年龄为9~54岁,平均(25.06±6.34)岁;吸毒时间平均(6.71±4.55)年;1 123例(49.65%)曾有毒品注射行为;81例(3.58%)注射毒品时有共用针具行为;MMT治疗维持时间平均(5.02±2.01)年;治疗期间平均服药剂量为(34.49±22.69)mL。MMT维持率为29.22%(661/2 262),门诊所在地区(OR:1.984~3.445)、患者年龄≥40岁(OR=1.640,95%CI:1.168~2.304)、治疗剂量>20 mL(OR:1.937~2.636)是MMT维持率的影响因素。结论 台州市MMT患者以男性、未婚、离异或丧偶、初中及以下文化程度为主;MMT维持率总体较低,≥40岁和治疗剂量>20 mL的患者MMT维持率相对较高。
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叶小红
柏鸿凌
许圆圆
吴琼海
沈伟伟
丁盈盈
林海江
关键词 美沙酮维持治疗海洛因成瘾维持率    
AbstractObjective To investigate the characteristics of methadone maintenance treatment(MMT)clients,and to explore their retention rate and associated factors in Taizhou,Zhejiang Province. Methods Heroin or opiate addicts who started MMT between 2006 and 2014 in study area were included. Data including demographics,history of drug use and treatment information was extracted from the National MMT Data Management System and descriptive analysis were conducted. Multiple logistic regression models were used to explore factors associated with retention rate. Results In total,2 262 MMT clients were included for analysis. Most of them were male(87.53%),single,divorced or widowed(55.75%),and had an education of junior middle school or below(88.68%). Almost all of them (98.32%)were heroin addicts,and the age at first drug use ranged from 9 years to 54 years,with average age of(25.06±6.34)years. A total of 1 123(49.65%)clients had a history of inject drug use and 81(3.58%)clients had ever shared needles with others. The average duration on MMT was 5.02±2.01 years,and the average methadone dosage during treatment was (34.49±22.69)mL. The MMT retention rate was 29.2%(661/2 262). In multivariable analysis,districts such as Huangyan District,Yuhuan County and Linhai City,aged≥40 years and average methadone dosage>20 mL during treatment were independently and positively associated with retention rate. Conclusion Most of MMT clients in Taizhou are male,unmarried,and had low education level. The retention rate is low in Taizhou but older patents and those receive high methadone dosage have a relatively higher retention rate.
Key wordsMethadone maintenance treatment    Heroin addiction    Retention rate
收稿日期: 2017-06-01      修回日期: 2017-08-14      出版日期: 2018-01-04
中图分类号:  R749.6  
基金资助:国家自然科学基金(81402725)
通信作者: 林海江,E-mail:linhaijiang@hotmail.com   
作者简介: 叶小红,硕士,副主任医师,主要从事传染病控制工作
引用本文:   
叶小红, 柏鸿凌, 许圆圆, 吴琼海, 沈伟伟, 丁盈盈, 林海江. 台州市美沙酮维持治疗人群特征分析[J]. 预防医学, 2018, 30(1): 5-8.
YE Xiao-hong*, BAI Hong-ling, XU Yuan-yuan, WU Qiong-hai, SHEN Wei-wei, DING Ying-ying, LIN Hai-jiang. Characteristics of patients on methadone maintenance treatment in Taizhou City. Preventive Medicine, 2018, 30(1): 5-8.
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