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| Research progress on health economic evaluation of active case finding strategies for tuberculosis |
| YANG Jing, LI Jiarui, MOU Zhiruo, WANG Qingya
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| Chongqing Department of Tuberculosis Control and Prevention, Chongqing 400050, China |
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Abstract Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis, which can involve multiple organs throughout the body. The active case finding (ACF) strategy is an important approach for improving TB case detection among priority populations. In this review, literature on health economic evaluations of TB ACF strategies included in PubMed, CNKI and other databases was retrieved, and the health economic evidence of ACF strategies among different priority populations was reviewed, focusing on cost-effectiveness and cost-benefit assessments. Existing evidence indicates that ACF strategies may hold economic value in priority populations, with relatively prominent cost-effectiveness among close contacts of pulmonary tuberculosis patients and certain individuals living with HIV, whereas the evidence for elderly populations and populations in congregate settings remains relatively limited. The economic value of ACF strategies is influenced by target populations, screening methods, health resource conditions and other factors. Currently, most studies concentrate on the cost per case detected, lacking comprehensive evaluations of long-term health benefits and socioeconomic benefits. Future real-world health economic research across different populations and screening strategies should be strengthened, so as to provide the evidence for optimizing TB prevention and control strategies and resource allocation.
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Received: 12 March 2026
Revised: 04 August 2026
Published: 22 September 2026
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