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| Mortality and years of life lost of five major digestive system malignant tumors in Anji County from 2015 to 2025 |
| CAO Yi, DING Yang, DENG Fangyuan, LIU Jingjing
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| Anji County Center for Disease Control and Prevention (Anji County Institute of Public Health Supervision),Anji, Zhejiang 313000, China |
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Abstract Objective To analyze the mortality trends and years of life lost of five major digestive system malignant tumors in Anji County, Zhejiang Province, from 2015 to 2025, so as to provide reference for improving prevention and control measures for digestive system malignant tumors. Methods Data on deaths from digestive system malignant tumors among residents in Anji County from 2015 to 2025 were collected through Zhejiang Provincial Chronic Disease Surveillance Information Management System, and the crude mortality were calculated. Age-standardized mortality was calculated using data from the fifth National Population Census in 2000. Potential years of life lost (PYLL), average years of life lost (AYLL), and potential years of life lost rate (PYLLR) were used to analyze years of life lost. The average annual percent change (AAPC) was used to analyze the trends in mortality from digestive system malignant tumors from 2015 to 2025. Results From 2015 to 2025, a total of 4 133 deaths from digestive system malignant tumors were reported in Anji County. The crude mortality was 79.67/105, and the age-standardized mortality was 34.75/105. A total of 3 957 deaths were attributed to liver cancer, colorectal cancer, gastric cancer, pancreatic cancer, and esophageal cancer, accounting for 95.74% of all cancer-related deaths. The corresponding crude mortality were 19.68/105, 19.14/105, 16.25/105, 12.07/105, and 9.14/105, respectively. From 2015 to 2025, the age-standardized mortality of liver cancer, gastric cancer, esophageal cancer, and colorectal cancer showed downward trends (AAPC=-6.647%, -8.021%, -7.788%, and -2.087%, all P<0.05), while the trend for pancreatic cancer was not statistically significant (P>0.05). The crude mortality of liver cancer, colorectal cancer, gastric cancer, pancreatic cancer, and esophageal cancer in males were 27.19/105, 23.96/105, 23.85/105, 13.54/105, and 15.44/105, respectively, while the corresponding rates in females were 12.30/105, 14.40/105, 8.79/105, 10.62/105, and 2.94/105, respectively (all P<0.05). With increasing age, the mortality of liver cancer, colorectal cancer, gastric cancer, and esophageal cancer peaked in the ≥85 years age group, while pancreatic cancer peaked in the 80-<85 years age group. The PYLL of the five major digestive system malignant tumors was 16 015.00 person-years, the AYLL was 9.84 years per person, and the PYLLR was 3.48‰. Among them, liver cancer had relatively high PYLL (5 490.00 person-years), AYLL (10.98 years per person), and PYLLR (1.19‰). Conclusions From 2015 to 2025, the age-standardized mortality of liver cancer, colorectal cancer, gastric cancer, and esophageal cancer in Anji County generally declined, while that of pancreatic cancer remained relatively stable. Liver cancer recorded a relatively high years of life lost. Males and the elderly remain the key populations for prevention and control.
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Received: 17 March 2026
Revised: 06 July 2026
Published: 27 July 2026
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