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| Serotype and antimicrobial resistance of Salmonella in foodborne diseases in Danzhou City |
| YANG Na, YANG Qiurong, LIU Huimei, LI Ruyuan, LIU Jia, YANG Chu'ai, FU Chuantao
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| Danzhou Center for Disease Control and Prevention (Danzhou Institute of Public Health Supervision),Danzhou, Hainan 571700, China |
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Abstract Objective To investigate the serotypes and antimicrobial resistance profiles of Salmonella isolates from foodborne disease patients in Danzhou City, Hainan Province, so as to provide the evidence for improving regional prevention and control strategies for foodborne diseases. Methods Salmonella strains were isolated from stool or anal swab specimens of patients with foodborne diarrhea treated at Hainan Western Central Hospital and Danzhou People's Hospital from 2022 to 2025. After identification, slide agglutination tests were performed for serotyping. The microbroth dilution method was used to detect antimicrobial resistance of Salmonella strains. Results A total of 927 specimens were collected, and 87 Salmonella strains were isolated, with a detection rate of 9.38%. Nineteen serotypes were identified, dominated by Salmonella Typhimurium (35 strains, 40.23%), Salmonella Weltevreden (17 strains, 19.54%) and Salmonella Enteritidis (6 strains, 6.90%). Antimicrobial susceptibility testing showed that 64 strains were resistant, with an overall resistance rate of 73.56%, and 54 strains were multidrug-resistant, with a multidrug resistance rate of 62.07%. The resistance rate to tetracycline was relatively high at 65.52%. A total of 38 resistance patterns were identified, covering 1 to 8 antimicrobial agents. The predominant multidrug resistance patterns were chloramphenicol-trimethoprim-sulfamethoxazole-tetracycline-ampicillin-sulbactam and chloramphenicol-trimethoprim-sulfamethoxazole-tetracycline-streptomycin-ampicillin-sulbactam, identified in 8 (12.50%) and 5 (7.81%) isolates, respectively. Conclusions The predominant Salmonella serotypes isolated from foodborne disease patients in Danzhou City are Salmonella Typhimurium, Salmonella Weltevreden and Salmonella Enteritidis. The strains exhibit severe antimicrobial resistance and multidrug resistance, especially against tetracycline. It is necessary to strengthen antimicrobial resistance surveillance and promote rational use of antibiotics.
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Received: 07 January 2026
Revised: 11 May 2026
Published: 27 July 2026
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