Epidemiological characteristics and spatial clustering of hand-foot-mouth disease in Pingxiang City from 2013 to 2023
ZENG Yong1, LI Yilin1, WU Yaojian2
1. Anyuan District Center for Disease Control and Prevention, Pingxiang, Jiangxi 337000, China; 2. Pingxiang Center for Disease Control and Prevention, Pingxiang, Jiangxi 337000, China
Abstract：Objective To understand the epidemiological and spatial clustering characteristics of hand-foot-mouth disease in Pingxiang City, Jiangxi Province from 2013 to 2023, so as to provide the evidence for improving hand-foot-mouth disease prevention and control measures. Methods Data of hand-foot-mouth disease cases in Pingxiang City from 2013 to 2023 were collected from the Infectious Disease Reporting Information System of Chinese Disease Prevention and Control Information System. Demographic, temporal, and regional distribution characteristics were described. The trend in incidence was analyzed using the average annual percent change (AAPC). The spatial clustering and aggregation patterns of hand-foot-mouth disease were identified using global and local spatial autocorrelation analyses. Results A total of 58 020 hand-foot-mouth disease cases were reported in Pingxiang City from 2013 to 2023, with an average annual incidence of 289.71/105. No significant trend in the reported incidence of hand-foot-mouth disease was observed (AAPC=-7.398%, P>0.05). Among them, 33 892 were males and 24 128 were females, with infants aged 0-<3 years accounting for 70.59% of the total (40 958 cases). The peak incidence occurred mainly from May to June and from September to December. Luxi County had the highest average annual reported incidence of 677.10/105. Spatial autocorrelation analysis indicated significant spatial clustering of hand-foot-mouth disease in 2018, 2019, 2021, and 2022 (Moran's I=0.314, 0.339, 0.381, and 0.668, all P<0.05). High-high clustering areas were primarily identified in 7 townships (streets) of Anyuan District, 2 in Xiangdong District, 4 in Shangli County, and 1 in Luxi County. Conclusions The reported incidence of hand-foot-mouth disease in Pingxiang City from 2013 to 2023 remained stable overall, with higher susceptibility among young children and peak incidence during summer and autumn. Spatial clustering of hand-foot-mouth disease was observed, expanding northward and southwestward from Anyuan District as the core area.
曾勇, 李亦麟, 吴耀坚. 2013—2023年萍乡市手足口病流行特征和空间聚集性分析[J]. 预防医学, 2025, 37(11): 1175-1178,1183.
ZENG Yong, LI Yilin, WU Yaojian. Epidemiological characteristics and spatial clustering of hand-foot-mouth disease in Pingxiang City from 2013 to 2023. Preventive Medicine, 2025, 37(11): 1175-1178,1183.
[1] ZHU P Y,JI W Q,LI D,et al.Current status of hand-foot-and-mouth disease [J/OL].J Biomed Sci,2023,30(1)[2025-08-20].https://doi.org/10.1186/s12929-023-00908-4. [2] REN F R,CUI Z,ZHANG M,et al.Effects of meteorological factors and atmospheric pollution on hand,foot,and mouth disease in Urumqi Region[J/OL].Front Public Health,2022,10[2025-08-20].https://doi.org/10.3389/fpubh.2022.913169. [3] CUI Y,YANG Y N,ZHENG R R,et al.Epidemiological characteristics of hand,foot,and mouth disease clusters during 2016-2020 in Beijing,China[J].J Med Virol,2022,94(10):4934-4943. [4] LIU Z Y,LI X,LI X H,et al.Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection[J/OL].mBio,2025,16(2)[2025-08-20].https://doi.org/10.1128/mbio.03040-24. [5] 张鹏飞,许玲,冯秀,等.2013—2016年萍乡市手足口病流行特征分析[J].应用预防医学,2018,24(1):25-27. ZHANG P F,XU L,FENG X,et al.Epidemiological characteristics of hand-foot-mouth disease in Pingxiang City from 2013 to 2016[J].Appl Prev Med,2018,24(1):25-27.(in Chinese) [6] ZHANG X L,ZHANG Y F,LI H,et al.Hand-foot-mouth disease-associated enterovirus and the development of multivalent HFMD vaccines[J/OL].Int J Mol Sci,2022,24(1)[2025-08-20].https://doi.org/10.3390/ijms24010169. [7] GEDAMU W T,PLANK-WIEDENBECK U,WODAJO B T.A spatial autocorrelation analysis of road traffic crash by severity using Moran's I spatial statistics:a comparative study of Addis Ababa and Berlin cities[J/OL].Accid Anal Prev,2024[2025-08-20].https://doi.org/10.1016/j.aap.2024.107535. [8] 梁小洁,张智芳,王晓欢.中国大陆手足口病流行特征及空间聚集性分析[J].中国人兽共患病学报,2023,39(10):1009-1016. LIANG X J,ZHANG Z F,WANG X H.Spatio-temporal distribution of hand,foot and mouth disease in mainland China[J].Chin J Zoonoses,2023,39(10):1009-1016. (in Chinese) [9] 刘艳,张子喆,王雨达,等.2013—2023年湖州市手足口病流行特征[J].预防医学,2025,37(7):718-721. LIU Y,ZHANG Z Z,WANG Y D,et al.Epidemiological characteristics of hand,foot,and mouth disease in Huzhou City from 2013 to 2023[J].China Prev Med J,2025,37(7):718-721.(in Chinese) [10] 庞志峰,金祝平,章光明,等.2011—2017年浙江省金华市手足口病流行特征分析[J].疾病监测,2019,34(1):53-56. PANG Z F,JIN Z P,ZHANG G M,et al.Epidemiological characteristics of hand,foot and mouth disease in Jinhua,Zhejiang,2011-2017[J].Dis Surveill,2019,34(1):53-56.(in Chinese) [11] 肖文强,包凯芳,李保军,等.2011—2022年海曙区手足口病流行特征[J].预防医学,2024,36(11):976-979. XIAO W Q,BAO K F,LI B J,et al.Epidemiological characteristics of hand,foot,and mouth disease in Haishu District from 2011 to 2022[J].China Prev Med J,2024,36(11):976-979.(in Chinese) [12] 王唐,董兆鹏,李淑华,等.金山区托幼机构和学校手足口病聚集性疫情分析[J].预防医学,2023,35(9):800-802. WANG T,DONG Z P,LI S H,et al.Epidemiological characteristics of hand,foot and mouth disease clusters in kindergartens and schools in Jinshan District[J].China Prev Med J,2023,35(9):800-802.(in Chinese) [13] ZOU Q,SHI X F,LIANG C W,et al.Impact of kindergarten structures on the dynamics of hand,foot,and mouth disease and the effects of intervention strategies:an agent-based modeling study[J/OL].BMC Med,2025,23(1)[2025-08-20].https://doi.org/10.1186/s12916-025-04207-7.
