Abstract：Objective To investigate the prevalence of osteoporosis (OP) and its influencing factors among people aged 60 years and above, so as to provide insights into OP prevention and treatment among the elderly. Methods People aged 60 years and above who underwent physical examinations were selected from Hangzhou First People's Hospital from January to October 2023. Demographic information, lifestyle and physical examination data were collected through field surveys and hospital information systems. Bone density was measured by dual-energy X-ray densitometer, and OP was diagnosed with reference to the Guidelines for the Diagnosis and Treatment of Primary Osteoporosis (2022). Factors affecting the OP were identified using a multivariable logistic regression model. Results A total of 482 participants were included and had a mean age of (69.10±6.52) years. There were 217 men (45.02%) and 265 women (54.98%). The prevalence of OP was 43.36%. Multivariable logistic regression analysis identified gender (women, OR=3.791, 95%CI: 1.726-8.314), age (70 to 79 years, OR=1.260, 95%CI: 1.018-1.559; 80 years and above, OR=3.083, 95%CI: 1.546-6.147), body mass index (≥24 kg/m2, OR=0.358, 95%CI: 0.205-0.626), family history of fracture (OR=1.475, 95%CI: 1.073-2.030), diabetes (OR=1.626, 95%CI: 1.109-2.382), regular exercise (OR=0.457, 95%CI: 0.287-0.726), intake of milk products (OR=0.511, 95%CI: 0.335-0.780), intake of calcium supplements (OR=0.473, 95%CI: 0.287-0.778) and vitamin D deficiency (OR=2.132, 95%CI: 1.309-3.473) as factors affecting OP. Conclusion The prevalence of OP is associated with gender, age, body mass index, family history of fracture, diabetes, diet and vitamin D deficiency.
[1] 中华医学会物理医学与康复学分会,中国老年学和老年医学学会骨质疏松康复分会.原发性骨质疏松症康复干预中国专家共识[J].中华物理医学与康复杂志,2019,41(1):1-7. [2] 国家统计局.第七次全国人口普查公报(第五号)——人口年龄构成情况[EB/OL].[2024-02-04].http://www.stats.gov.cn/tjsj/tjgb/rkpcgb/qgrkpcgb/202106/t20210628_1818824.html. [3] 朱洁云,高敏,宋秋韵,等.中国老年人骨质疏松症患病率的Meta分析[J].中国全科医学,2022,25(3):346-353. [4] WANG X,LI C M,HE Y,et al.Anti-osteoporosis medication treatment pattern after osteoporotic fracture during 2010-2016 in Fujian,China[J].Arch Osteoporos,2020,15(1):1-11. [5] XIAO P L,CUI A Y,HSU C J,et al.Global,regional prevalence,and risk factors of osteoporosis according to the World Health Organization diagnostic criteria:a systematic review and meta-analysis[J].Osteoporos Int,2022,33(10):2137-2153. [6] 王雨荷,刘红,李艳,等.中国原发性骨质疏松症危险因素的Meta分析[J].中国骨质疏松杂志,2021,27(12):1730-1738. [7] 中华医学会骨质疏松和骨矿盐疾病分会,章振林.原发性骨质疏松症诊疗指南(2022)[J].中国全科医学,2023,26(14):1671-1691. [8] 周柳娇,李吉,雷钧.中老年人群骨质疏松症影响因素分析[J].预防医学,2021,33(2):188-191. [9] 高玉婕,陈晓云,沙艳梅,等.大理白族自治州女性绝经后骨质疏松的影响因素分析[J].预防医学,2022,34(4):419-423,428. [10] 汤淑女,尹香君,余卫,等.中国40岁及以上绝经后女性骨质疏松症患病率及其影响因素研究[J].中华流行病学杂志,2022,43(4):509-516. [11] 吴惠一,刘颖,兰亚佳,等.中国绝经女性骨质疏松症患病率的Meta分析[J].中国循证医学杂志,2022,22(8):882-890. [12] 朱蓉蓉,周文娟,刘秀敏.海安市农村地区老年人骨质疏松性骨折患病情况及相关因素分析[J].实用预防医学,2023,30(10):1260-1263. [13] 王剑,鲁敏,孙官文,等.呼和浩特地区40~65岁中老年女性骨质疏松症的流行现状及相关因素分析[J].中国医药,2020,15(4):601-605. [14] 刘斌,董芬,任晓岚,等.甘肃省20~80岁和绝经后女性骨质疏松症患病影响因素分析[J].中国骨质疏松杂志,2018,24(5):656-663. [15] 刘天资,郑启文,杨鹏,等.骨质疏松症的遗传及表观遗传因素[J].中华骨与关节外科杂志,2021,14(10):856-860. [16] WANG L,ZHANG D,XU J.Association between the Geriatric Nutritional Risk Index,bone mineral density and osteoporosis in type 2 diabetes patients[J].J Diabetes Investig,2020,11(4):956-963. [17] 吴志建,王竹影,宋彦李青,等.运动锻炼干预对我国中老年女性骨密度影响的meta分析[J].首都体育学院学报,2019,31(1):91-96. [18] KISTLER-FISCHBACHER M,WEEKS B K,BECK B R.The effect of exercise intensity on bone in postmenopausal women(part 2):a meta-analysis[J].Bone,2021,143:1-22. [19] 陈艳,陈佳力,张志爽,等.杭州市城区35岁以上体检人群骨质疏松症影响因素研究[J].预防医学,2023,35(2):137-140.
