Abstract：Objective To investigate the quality of life among people living with HIV/AIDS in Hangzhou City and analyze the influencing factors, so as to provide insights into the control of AIDS. Methods From 1 January 2014 to 30 June 2018, the demographic characteristics, medical expenditures and disease status were collected from HIV/AIDS patients living in Hangzhou City, and the quality of life was assessed using the simplified Chinese version of Medical Outcomes Study-HIV Health Survey ( MOS-HIV ). Factors affecting the quality of life were identified among HIV/AIDS patients using multivariable linear regression analysis. Results A total of 2 808 HIV/AIDS patients were surveyed, including 1 684 cases with HIV infections and 1 124 cases with AIDS. The participants included 2 510 men ( 89.39% ) and 298 women ( 10.61% ), and were predominantly at ages of 25 to 39 years ( 1 531 cases, 54.52% ). The physical and mental health scores were 53.87±6.96 and 46.03±9.09, respectively. Multivariable linear regression analysis identified age, average monthly income, self-paid medical expenses during the past year, and the latest CD4+T cell count as factors affecting physical and mental health ( P<0.05 ). Conclusions The quality of life is low among people living with HIV/AIDS in Hangzhou City, and is associated with age, income, medical expenditures and CD4+T cell count.
张兴亮, 陈珺芳, 许珂, 吴虹, 黄思超. 杭州市HIV/AIDS病例生活质量调查及影响因素分析[J]. 预防医学, 2022, 34(1): 27-32.
ZHANG Xingliang, CHEN Junfang, XU Ke, WU Hong, HUANG Sichao. Quality of life and its influencing factors among people living with HIV/AIDS in Hangzhou City. Preventive Medicine, 2022, 34(1): 27-32.
[1] DANFORTH K,GRANICH R,WIEDEMAN D,et al.Global mortality and morbidity of HIV/AIDS[M]//Major infectious diseases.3rd ed.Washington.D.C.:The International Bank for Reconstruction and Development/The World Bank,2017:29-44. [2] PEDERSEN K K,EIERSTED M R,GAARDBO J C,et al.Lower self-reported quality of life in HIV-infected patients on cART and with low comorbidity compared with healthy controls[J].J Acquir Immune Defic Syndr,2015,70(1):16-22. [3] LAZARUS J V,KELLY S H,BARTON S E,et al.Beyond viral suppression of HIV-the new quality of life frontier[J].BMC Med,2016,14(1):94-98. [4] 薛建,程晓松,林荣,等.烟台市HIV/AIDS病例生命质量及影响因素分析[J].预防医学,2019,31(5):493-498. XUE J,CHENG X S,LIN R,et al.Quality of life and its influencing factors among people living with HIV/AIDS in Yantai[J].Prev Med,2019,31(5):493-498. [5] ANDERSSON G Z,REINIUS M,ERIKSSON L E,et al.Stigma reduction interventions in people living with HIV to improve health-related quality of life[J].The Lancet HIV,2020,7(2):e129-e140. [6] MARCUS J L,LEYDEN W A,ALEXEEFF S E,et al.Comparison of overall and comorbidity-free life expectancy between insured adults with and without HIV infection,2000-2016[J].JAMA Netw Open,2020,3(6):1-12. [7] 喻达,刘民,明中强.MOS-HIV量表简体中文版的翻译、修订及信度效度评价[J].中国艾滋病性病,2008,14(5):454-456. YU D,LIU M,MING Z Q.Reliability and validity of the Chinese version of MOS-HIV among HIV-infected individuals receiving HAART[J].Chin J AIDS STD,2008,14(5):454-456. [8] WU A W.MOS-HIV health survey users manual[M].Birminghan:Johns Hopkins University Press,1996:20-32. [9] 董选军,楼莲青,陈黎,等.中文版MOS-HIV量表信度和效度分析[J].中国卫生统计,2015,32(4):619-620. DONG X J,LOU L Q,CHEN L,et al.Reliability and validity of the Chinese version of MOS-HIV[J].Chin J Health Stat,2015,32(4):619-620. [10] 吴丽萍,刘林飞,胡锦流,等.淮安市HIV感染者/AIDS患者生存质量调查及其影响因素[J].职业与健康,2014,30(17):2412-2415. WU L P,LIU L F,HU J L,et al.Investigation on quality of life among HIV infection/AIDS patients in Huai'an City and analysis on influencing factors[J].Occup Health,2014,30(17):2412-2415. [11] 隋丹丹,林鹏,陈抒豪,等.179例艾滋病病毒感染者及艾滋病患者生存质量研究[J].华南预防医学,2015,41(2):117-123. SUI D D,LIN P,CHEN S H,et al.Quality of life of 179 patients infected with HIV[J].South China J Prev Med,2015,41(2):117-123. [12] 董晓梅,彭淋,张思恒,等.广东省HIV感染者/艾滋病患者生活质量及其影响因素分析[J].中华流行病学杂志,2014,35(1):40-44. DONG X M,PENG L,ZHANG S H,et al.Quality of life and related factors among people living with HIV/AIDS in Guangdong province[J].Chin J Epidemiol,2014,35(1):40-44. [13] VAN DER KOP M L,MUHULA S,PATEL A,et al.Gender differences in health-related quality of life at the time of a positive HIV test-a cross-sectional study in a resource-poor,high prevalence setting in Nairobi,Kenya[J].AIDS Care,2018,30(4):493-499. [14] 冯世艳,邵冰,宋波,等.哈尔滨主要HIV感染人群生存质量及其影响因素分析[J].哈尔滨医科大学学报,2017,51(1):78-86. FENG S Y,SHAO B,SONG B,et al.Analysis of life quality of major HIV infected people in Harbin and its influencing factors[J].J Harbin Med Univ,2017,51(1):78-86. [15] 孙燕,张雪,杨萱,等.河南省长期生存HIV/AIDS病人生存质量及其影响因素[J].中国艾滋病性病,2019,25(2):115-118. SUN Y,ZHANG X,YANG X,et al.Quality of life and influencing factors of long-term survival of HIV/AIDS patients in Henan province[J].Chin J AIDS STD,2019,25(2):115-118. [16] 景兴科,杨海峰.艾滋病患者心理社会因素与生存质量的相关性分析[J].预防医学,2017,29(7):724-726. JING X K,YANG H F.Correlation analysis of psychosocial factors and.quality of life in HIV/AIDS patients[J].Prev Med,2017,29(7):724-726. [17] 李松,刘爱文,李辉,等.安徽省艾滋病抗病毒治疗病人生活质量与社会支持典型相关分析[J].中华疾病控制杂志,2014,18(10):956-959. LI S,LIU A W,LI H,et al.Canonical correlation analysis of the quality of life with social support status among HIV/AIDS patients receiving antiretroviral treatment in Anhui Province,China[J].Chin J Dis Control Prev,2014,18(10):956-959. [18] UBEL P A,JAGSI R.Promoting population health through financial stewardship[J].N Engl J Med,2014,370(14):1280-1281. [19] 李世福,高良敏,蔡英,等.未治疗HIV/AIDS中CD4+T淋巴细胞计数与机会性感染的相关性分析[J].中国皮肤性病学杂志,2017,31(3):267-272. LI S F,GAO L M,CAI Y,et al.Correlational analysis between the CD4+T cell counts and opportunistic infection in HIV/AIDS patients with no antiretroviral treatment[J].Chin J Derm Venereol,2017,31(3):267-272.
