Abstract：Objective To analyze the status and trend of death from leukemia from 2006 to 2015 in Hangzhou,and to provide scientific basis for leukemia prevention and control. Methods The data of deaths in Hangzhou from 2006 to 2015 were collected from Zhejiang chronic diseases surveillance system. The crude mortality rates,standardized mortality rates and cumulative rates of the age group 0-74 of leukemia were calculated. The annual percentage change（APC）was used to examine the changing trend of leukemia mortality. Results The crude mortality rate of leukemia in Hangzhou was 4.38/100 000 and the standardized mortality rate was 3.79/100 000 from 2006 to 2015. The standardized mortality rates from 2006 to 2015 showed a decreasing trend and the APC was -2.27%（P<0.05）. The crude mortality rate of leukemia was 5.15/100 000 in males,which was higher than 3.62/100 000 in females（P<0.05）. The crude and standardized mortality rates were 2.00/100 000 and 0.45/100 000 in residents aged below 15 years,3.03/100 000 and 1.85/100 000 in residents aged 15-64 years,15.63/100 000 and 1.05/100 000 in residents aged 65 years or above. The standardized mortality rates of residents aged below 15 years and 15-64 years showed decreasing trends,the APCs were -9.24% and -3.82%,respectively（P<0.05）. The standardized mortality rates of residents aged 65 years or above showed an increasing trend,the APC was 3.77%（P<0.05）. Conclusion The standardized mortality rates of leukemia has presented a declining trend in Hangzhou from 2006 to 2015,with higher mortality in men and people aged 65 years or above.
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