Abstract：Objective To analyze the infection status of human papillomavirus (HPV) among women aged 35-64 years in Deqing County, Zhejiang Province, so as to provide a reference for the prevention and treatment of cervical lesions. Methods Women aged 35-64 years who underwent combined cervical cancer screening with HPV and ThinPrep cytologic test (TCT) at the Deqing County Maternal and Child Health and Family Planning Service Center from 2022 to 2024 were selected as study participants. The HPV infection rate and subtype distribution, positive rate of epithelial cell abnormalities, and positive rate of cervical lesions were analyzed. Results A total of 16 155 women were included, with the 55-<60 years age group being the most prevalent, accounting for 8 200 (50.76%). HPV infection was detected in 2 015 cases, with an infection rate of 12.47%. High-risk HPV infection was detected in 1 735 cases (86.10%), with an infection rate of 10.74%. Low-risk HPV infection was detected in 280 cases (13.90%), with an infection rate of 1.73%. The top three HPV subtypes with the highest infection rates were HPV52, 58, and 16, with infection rates of 3.46%, 1.84%, and 1.18%, respectively. The rates of high-risk HPV infection, single infection, and multiple infection all showed an upward trend with increasing age (all P<0.05), peaking in the group aged 60-64 years, at 13.26%, 10.96%, and 2.30%, respectively. The positive rate of cervical epithelial cell abnormalities in women with high-risk HPV infection was higher than in women with low-risk HPV infection (27.43% vs. 2.86%, P<0.05). Among them, the positive rates of low-grade squamous intraepithelial lesions and atypical squamous cells of undetermined significance were higher in women with high-risk HPV infection than in women with low-risk HPV infection (both P<0.05). Cervical lesions were detected in 150 cases, with a positive rate of 8.65%. Conclusions The HPV infection rate among women aged 35-64 years in Deqing County was at a moderate level nationally, with HPV52, 58, and 16 being the predominant subtypes. The infection rate increases with age, highlighting the need for enhanced cervical lesions screening among women with high-risk HPV infection.
陈建元, 徐国琴, 姚云蕾. 德清县女性人乳头瘤病毒感染状况分析[J]. 预防医学, 2026, 38(4): 429-432.
CHEN Jianyuan, XU Guoqin, YAO Yunlei. Human papillomavirus infection status among women in Deqing County. Preventive Medicine, 2026, 38(4): 429-432.
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