Abstract：Objective To investigate the epidemiological characteristics of epidemic encephalitis B in Huzhou City, Zhejiang Province from 2007 to 2023, so as to provide the evidence for formulating prevention and control measures for epidemic encephalitis B. Methods Epidemic encephalitis B case data in Huzhou City from 2007 to 2023 were collected through the National Notifiable Disease Reporting System of the Chinese Disease Prevention and Control Information System. The temporal, regional and population distribution characteristics of laboratory-confirmed epidemic encephalitis B cases were analyzed using the descriptively epidemiological method. Results A total of 49 laboratory-confirmed epidemic encephalitis B cases were reported in Huzhou City from 2007 to 2023, and the average annual incidence was 0.10/105, showing a significant downward trend (P<0.05). The epidemic encephalitis B cases were concentrated from July to August, and July was the peak month, with 40 cases accounting for 81.63%. There was a statistically significant difference in the average annual incidences of epidemic encephalitis B among counties (districts) (P<0.05). Nanxun District had the highest reported incidence, with an average annual incidence of 0.23/105. There were 30 male cases and 19 female cases, with a male-to-female ratio of 1.58∶1. The youngest case was 5 months old, and the oldest was 49 years old. The children under 15 years were in the majority, with 42 cases accounting for 85.71%. Most of the cases were scattered children, with 25 cases accounting for 51.02%. There were 22 cases with no vaccination history and 21 cases with an unknown vaccination history, accounting for 44.90% and 42.86% respectively. All cases presented with fever. Other main clinical symptoms included listlessness, drowsiness, vomiting and headache, with 47, 40, 33 and 29 cases respectively, accounting for 95.92%, 81.63%, 67.35% and 59.18%, respectively. Conclusions The incidence of epidemic encephalitis B in Huzhou City remained at a relatively low level from 2007 to 2023, with Nanxun District being the high-risk area and July being the peak month for disease incidence. Fever and listlessness were the predominant clinical manifestations. Strengthening vaccination for children under 15 years should be prioritized.
张超, 沈建勇, 罗小福, 刘艳, 韩利萍. 2007—2023年湖州市流行性乙型脑炎流行特征[J]. 预防医学, 2025, 37(4): 386-389.
ZHANG Chao, SHEN Jianyong, LUO Xiaofu, LIU Yan, HAN Liping. Epidemiological characteristics of epidemic encephalitis B in Huzhou City from 2007 to 2023. Preventive Medicine, 2025, 37(4): 386-389.
[1] 闫婷婷,吴丹,郑徽,等.中国2019—2022年流行性乙型脑炎流行病学特征[J].中国疫苗和免疫,2024,30(2):160-164. YAN T T,WU D,ZHENG H,et al.Epidemiology of Japanese encephalitis in China,2019-2022[J].Chin J Vaccines Immunization,2024,30(2):160-164.(in Chinese) [2] GRIFFITHS M J,TURTLE L,SOLOMON T.Japanese encephalitis virus infection[J].Handb Clin Neurol,2014,123:561-576. [3] DENG X,YAN J Y,HE H Q,et al.Serological and molecular epidemiology of Japanese encephalitis in Zhejiang,China,2015-2018[J].PLoS Negl Trop Dis,2020,14(8):1-19. [4] 邓璇,严睿,唐学雯,等.浙江省流行性乙型脑炎流行病学特征分析[J].预防医学,2017,29(10):994-998. DENG X,YAN R,TANG X W,et al.Epidemiological characteristics of epidemic encephalitis B in Zhejiang Province[J].China Prev Med J,2017,29(10):994-998.(in Chinese) [5] 中华人民共和国卫生部.全国流行性乙型脑炎监测方案[S].2006. Ministry of Health of the People's Republic of China.National surveillance program for Japanese encephalitis surveillance[S].2006.(in Chinese) [6] 吴晓虹,施红喜,唐慧玲.浙江省金华市2007—2012年流行性乙型脑炎流行病学特征分析[J].中国媒介生物学及控制杂志,2013,24(6):549-551. WU X H,SHI H X,TANG H L.Epidemiological characteristics of Japanese encephalitis in Jinhua,China from 2007 to 2012[J].Chin J Vector Biol & Control,2013,24(6):549-551.(in Chinese) [7] 孙肖瑜,郑晓春,魏晶娇,等.2016—2020年温州市流行性乙型脑炎流行特征分析[J].预防医学,2021,33(9):919-920. SUN X Y,ZHENG X C,WEI J J,et al.Epidemiological characteristics of epidemic encephalitis B in Wenzhou City from 2016 to 2020[J].China Prev Med J,2021,33(9):919-920.(in Chinese) [8] 任飞林,沈建勇,刘婷,等.布雷图指数法与诱蚊诱卵指数法监测白纹伊蚊幼虫密度相关性分析[J].疾病监测,2021,36(9):888-893. REN F L,SHEN J Y,LIU T,et al.Correlation between Breteau index and mosquito oviposition index in surveillance for Aedes albopictus larvae density[J].Dis Surveill,2021,36(9):888-893.(in Chinese) [9] 冀彤,马菊红,张学太.2017—2021年白银市国家级监测点蚊类监测分析[J].中华卫生杀虫药械,2023,29(4):354-357. JI T,MA J H,ZHANG X T.Analysis of mosquito surveillance data from national monitoring sites in Baiyin from 2017 to 2021[J].Chin J Hyg Insect & Equip,2023,29(4):354-357.(in Chinese) [10] 刘丽珺,漆琪,刘宇,等.2015—2018年四川省542例流行性乙型脑炎病例流行病学特征分析[J].现代预防医学,2020,47(8):1345-1348. LIU L J,QI Q,LIU Y,et al.Characteristics of 542 Japanese encephalitis cases in Sichuan Province from 2015 to 2018[J].Mod Prev Med,2020,47(8):1345-1348.(in Chinese) [11] 罗兴,李丹,尹钟亿,等.2005—2020年广元市流行性乙型脑炎病例流行病学特征分析[J].寄生虫病与感染性疾病,2022,20(1):22-26. LUO X,LI D,YIN Z Y,et al.Epidemiological characteristics of Japanese encephalitis in Guangyuan from 2005 to 2020[J].Parasitoses Infect Dis,2022,20(1):22-26.(in Chinese) [12] 蒋凤,梁禄祥,芮莉萍,等.2007—2019年贵州省流行性乙型脑炎流行病学特征[J].中国疫苗和免疫,2020,26(3):280-282. JIANG F,LIANG L X,RUI L P,et al.Epidemiological characteristics of Japanese encephalitis in Guizhou province,2007-2019[J].Chin J Vaccines Immunization,2020,26(3):280-282.(in Chinese) [13] 陈斐,李亚飞,刘素华.2005—2021年河南省平顶山市流行性乙型脑炎特征和发病热点地区[J].现代疾病预防控制,2023,34(11):836-840. CHEN F,LI Y F,LIU S H.Characteristics and hot spots of Japanese encephalitis in Pingdingshan,Henan,2005-2021[J].Mod Dis Contr Prev,2023,34(11):836-840.(in Chinese) [14] 闫文喆,李晋宇,郭玉红,等.我国流行性乙型脑炎流行特征及其病毒基因型研究进展[J].中国媒介生物学及控制杂志,2024,35(6):744-752. YAN W Z,LI J Y,GUO Y H,et al.Research progress on the epidemic characteristics and virus genotypes of Japanese encephalitis in China[J].Chin J Vector Biol & Control,2024,35(6):744-752.(in Chinese) [15] 付思成,郭小熙,贵春燕,等.甘肃省≥15岁人群接种乙型脑炎减毒活疫苗的成本效用分析[J].中国疫苗和免疫,2024,30(4):485-491. FU S C,GUO X X,GUI C Y,et al.Cost-utility analysis of Japanese encephalitis vaccination among individuals ≥15 years of age in Gansu province[J].Chin J Vaccines Immunization,2024,30(4):485-491.(in Chinese)
