Abstract：Overweight and obesity are main risk factors for chronic metabolic diseases, and are strongly associated with the increased risk of premature death. Low carbohydrate diet (LCD) has been proven to effectively control body weight and fat mass in overweight and obese patients by short-term (≤6 months) dietary intervention studies. The mechanisms include regulation of energy metabolism, anti-inflammatory, antioxidant, alteration in expression of lipid metabolic-related genes and modulation of intestinal flora. However, the conclusions are inconsistent on whether LCD can cause durable weight loss and reduce the risk of overweight and obesity. This review summarizes the current research progress on the mechanisms, epidemiological studies, intervention studies and potential risks of LCD in controlling overweight and obesity, providing a reference for the future research and clinical application.
陆彦妤, 郭惠兰, 沈放, 黄晓旭, 张片红. 低碳水化合物饮食控制超重肥胖的研究进展[J]. 预防医学, 2021, 33(12): 1231-1235.
LU Yanyu, GUO Huilan, SHEN Fang, HUANG Xiaoxu, ZHANG Pianhong. Research progress on low carbohydrate diet in the control of overweight and obesity. Preventive Medicine, 2021, 33(12): 1231-1235.
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