Abstract：Objective To learn the changes of blood lead levels and serum biochemical parameters of the school age children from different areas. Methods All research objects,the school age children,were from three different areas respectively,including a mountainous area （L area）,an island area （H area） where there is not history of Pb pollution,and an industry area （N area） in relation to Pb pollution. The morning urine and peripheral venous blood samples were collected from the school age children. Pb in blood （PbB）,δ-aminoaevulinic acid in urine （ALA）,Ca2+,BUN,Cr in serum,and Thyroid Stimulating Hormone （TSH）,thyroxin （T4）,free thyroxin （FT4） levels were detected. Results PbB levels [M was 36.0 ppb] of the school age children from N area were significantly higher than that of L area [22.0 ppb] and H area [23.8 ppb]. On the contrary,serum Ca2+ levels of the school age children from N area were significantly lower than that of L area and H area. Serum T4 of N area was significantly lower than that of L area and H area. Serum FT4 of H area was significantly higher than that of L area and N area. And TSH of N area and H area were both obviously lower than that of L area. But all of these thyroxin indexes were in the range of normal values. Conclusion It should be widely concerned that the significant elevation of PbB levels may have a negative impact on school age children in the future.
蔡德雷, 孟真, 汤, 张世鑫, 徐彩菊, 宋燕华. 不同地区10~11岁儿童血铅水平和相关血清学指标研究[J]. 预防医学, 2017, 29(5): 449-451.
CAI De-lei, MENG Zhen, TANG Jun, ZHANG Shi-xing, XU Cai-ju, SONG Yan-hua. A study on the change of levels of blood lead and serum biochemical parameters of the school age children from different areas. Preventive Medicine, 2017, 29(5): 449-451.
