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预防医学  2017, Vol. 29 Issue (6): 545-549    DOI: 10.19485/j.cnki.issn1007-0931.2017.06.002
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PET/CT技术在非典型脊柱结核诊断中的应用
程爱萍, 傅立平, 孙美玲, 付涧兰, 王晓刚, 宋法寰
浙江省人民医院核医学科,浙江 杭州 310000
The application of the PET/CT technology in the diagnosis of atypical spinal tuberculosis
CHENG Ai-ping, FU Li-ping, SUN Mei-ling, FU Jian-lan, WANG Xiao-gang, SONG Fa-huan
Department of Nuclear Medicine,Zhejiang Provincial People's Hospital,Hangzhou,Zhejiang,310000,China
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摘要 目的 分析PET/CT技术在非典型脊柱结核影像诊断中的作用。方法 收集2010—2016年因脊柱病变在浙江省人民医院行PET/CT检查的60例患者的X光片、CT及PET/CT检查资料,以病理诊断为金标准,采用ROC曲线比较这3种诊断方法的准确性,并描述PET/CT检查的影像学特征。结果 60例患者中,男性52例,女性8例;年龄38~82岁,平均50.2岁。3种影像诊断的统计分析结果显示,PET/CT诊断脊柱结核灵敏度为0.850,特异度为0.950,诊断准确性最高(AUC=0.900,P<0.05);PET/CT融合解剖和功能检查,可发现病灶内存在放射性“冷区”、椎旁“放射性冷脓肿”等特征性表现。PET/CT影像可分为单脊椎型结核、椎间盘型结核和多发性脊柱结核3种类型。结论 采用PET/CT技术诊断非典型脊柱结核的准确性高于X线和CT,在难以诊断或怀疑脊柱转移瘤患者中值得推广应用。
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程爱萍
傅立平
孙美玲
付涧兰
王晓刚
宋法寰
关键词 脊柱结核PET/CTROC曲线    
AbstractObjective To explore the diagnostic value of PET/CT technique in the atypical spinal tuberculosis. Methods A total of 60 patients who had suffered from spinal tuberculosis and spinal metastasis confirmed by surgical interventions from 2010 to 2016 were retrospectively analyzed. 18F-FDG PET/CT examination was made at our department. Image data of X-ray,CT,and PET/CT were compared in the diagnosis accuracy. Results A total of 52 males and 8 females,aged from 38 to 82 years (mean,50.2 years) were collected. The statistical analysis showed PET/CT technology with sensitivity of 85%,and specificity of 95%,which were significantly higher than those of X-ray and CT(AUC=0.900,P<0.05). 18F-FDG PET/CT can find more lesions than X-ray and CT,find “cold abscess” and “cold zone” of spinal tuberculosis,that was an exclusive value of PET/CT diagnosis for atypical spinal tuberculosis. Conclusion 18F-FDG PET/CT shows an important clinical diagnostic value for the atypical spinal tuberculosis.
Key wordsSpinal tuberculosis    PET/CT    ROC curve
收稿日期: 2017-02-14      修回日期: 2017-02-28      出版日期: 2017-06-10
中图分类号:  R285.5  
通信作者: 程爱萍,E-mail:chengaiping68@126.com   
作者简介: 程爱萍,博士,副主任医师,主要从事核医学研究工作
引用本文:   
程爱萍, 傅立平, 孙美玲, 付涧兰, 王晓刚, 宋法寰. PET/CT技术在非典型脊柱结核诊断中的应用[J]. 预防医学, 2017, 29(6): 545-549.
CHENG Ai-ping, FU Li-ping, SUN Mei-ling, FU Jian-lan, WANG Xiao-gang, SONG Fa-huan. The application of the PET/CT technology in the diagnosis of atypical spinal tuberculosis. Preventive Medicine, 2017, 29(6): 545-549.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn1007-0931.2017.06.002      或      http://www.zjyfyxzz.com/CN/Y2017/V29/I6/545
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