Abstract：Objective To investigate the outbreak of one case of noruvirus gastroenteritis in a community hospital.Methods Field epidemiology investigation was conducted using a standard questionnaire. RT-PCR was used for detection.Results A total of 16 cases werereported during the outbreak, and the incidence rate was 28.07%.The incidence rate was 30% (9/30) among patients in the same inpatient area, and the incidence rate was 46.67%(7/15) among nursing worker in this inpatient area. There were no medical personnel affected. Fifteen out of 16 anal swab specimens were positive using a RT-PCR method, and hand hygiene of medical personnel and nursing workers were 100% and 33.33% qualified, respectively.Conclusion This gastroenteritis outbreak in healthcare setting was caused by norovirus GII. Nursing workers played an important role in the disease transmission.
[1]LOPMAN B,VENNEMA H, KOHLI E,et al. Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirns variant .J Lancet, 2004, 363 (9410):682-688.
[2]BLANTON L H, ADAMS S M, BEARD R S, et al. Molecular and epidemiologic trends of caliciviruses associated with outbreak of acute gastroenteritis in the United States( 2000-2004 ). J infect Dis,2006, 193(3): 413-421.
[3]贾立平,钱渊,张又,等.北京市某些医院内腹泻暴发与诺如病毒的相关性研究.中华流行病学杂志,2007,28(3):213-217.
[4]YODA T, SUZUKI Y, YAMAZAKI K, et al. Evaluation and application of reverse transcription loop-mediate disothermal amplification for detection of norovirnses. J Med Virol, 2007, 79(3):326-334.
[5]中国疾病预防控制中心.诺如病毒急性胃肠炎的诊断治疗和疑似暴发疫情的判定标准(2007- 01- 11).http://www.chinacdc.cn/jkzt/crb/nrbdjxwcy/jszl_2273/200701/t20070111_24754.htm.
[6]方杭燕,谢立,干伟群,等. I型诺如病毒引起学校急性胃肠炎爆发的调查.浙江预防医学, 2010,22(10):53-54.
[7]刘运喜,刘丽娟,索继江,等.一起老年病区诺如病毒医院感染暴发的调查.中华医院感染学杂志,2011,21 (6): 1136-1138.
[8]钱子煜,张越文,周祺,等.一起医院内集聚性诺如病毒胃肠炎的调查.中华医院感染学杂志,2012,22(12): 2573-2575.
[9]李海燕,蒋搏,孙志军,等.医院感染诺如病毒肠炎的流行病学调查.中华医院感染学杂志, 2009,19(2):166-167.
[10]钟文龙,傅深省,王莉,等. 1起老年精神病区诺如病毒感染暴发的调查.中国民康医学,2012,24(13):1635-1636,1642.
[11]倪晓,项海清,徐虹,等.诺如病毒医院内消毒隔离措施的制定与实施 .中国预防医学杂志,2008,9(5):377-379.
[12]TALUKDER K A, ISLAM Z, DUTTA D K,et al. Antibiotic resistance and genetic diversity of Shigella sonnei isolated from patients with diarrhea between 1999 and 2003 in Bangladesh. Med Microbiol, 2006,55(pt9):1257-1263.
[13]桑少伟,赵仲堂,索继江,等.国内诺如病毒胃肠炎暴发流行特征分析.中华医院感染学杂志,2011,21(20):Ⅰ-Ⅲ.
[14]徐潜.医院诺如病毒胃肠炎的流行与控制.中国医学科学院学报, 2008, 30(5):614 -617.
