Surveillance of soil-borne nematodiasis among rural populations in Tiantai County
CUI Qingrong1, HU Haiyan1, LUO Saifei1, RUAN Wei2, PANG Tianlan1, CHEN Dingling1
1. General Office, Tiantai Center for Disease Control and Prevention, Tiantai, Zhejiang 317200, China; 2. Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China
Abstract：Objective To investigate the prevalence of soil-borne nematode infections among rural residents in Tiantai County, Zhejiang Province, so as to provide insights into improving the control strategy. Methods According to the Zhejiang Provincial Surveillance Programme on Soil-borne Nematodiasis and Clonorchiasis, 5 administrative villages were randomly selected in Tiantai County according to geographical locations on April, 2021, and all permanent residents at ages of 3 years and older were sampled from each village using a cluster sampling method. Subjects' gender, age, occupation, education level and deworming were collected. Subjects' stool samples were collected, and soil-borne nematode eggs were detected using the modified Kato-Katz technique, and larval culture was performed using a filter-paper culture method among hookworm egg positives for identification of hookworm species. In addition, the intensity of infection was evaluated using hookworm eggs per gram stool sample. Results A total of 1 013 residents participated in the survey, including 495 men (48.86%) and 518 women (51.14%), and there were 502 participants at ages of 51 to 70 years (49.56%), 874 farmers (86.28%) and 436 subjects with an education level of primary school (43.04%). However, no subjects received deworming. The prevalence of hookworm infections was 3.85% among the study subjects, and only Necator americanus was identified. There were 31 cases with mild infections (79.49%), 5 cases with moderate infections (12.82%) and 3 cases with severe infections (7.69%), and all infections occurred in farmers. The prevalence of hookworm infections was 3.84% among men and 3.86% among women. No hookworm infection was detected among residents at ages of <41 years, and the prevalence of hookworm infections appeared a tendency towards a rise with age among residents at ages of 51 years and older (χ2trend=24.091, P<0.001), while the prevalence of hookworm infections appeared a tendency towards a decline with educational levels among residents (χ2trend=19.534, P<0.001). The greatest prevalence of hookworm infections was found in Qianyang Village (10.95%). Conclusions Hookworm disease is the predominant type of soil-borne nematodiasis in Tiantai County, and the middle-aged and elderly farmers with a low education level are high-risk populations for soil-borne nematodiasis control.
[1] 姚立农,阮卫,余可根,等.浙江省人体土源性线虫病调查及防治效果分析[J].疾病监测,2012,27(6):459-461. YAO L N,RUAN W,YU K G,et al.Survey of prevention and treatment of human intestinal parasitic diseases in Zhejiang[J].Dis Surveill,2012,27(6):459-461. [2] 周晓农. 2015年全国人体重点寄生虫病现状调查报告[M].北京:人民卫生出版社,2018. ZHOU X N.Report on thenational survey of important huamn parasitic diseases in China[M].Beijing:People's Medical Publishing House,2018. [3] 中华人民共和国国家卫生和计划生育委员会.肠道蠕虫检测改良加藤厚涂片法:WS/T 570—2017[S].2017. National Health and Family Planning Commission of People's Republic of China.Detection of intestinal helminths-the Kato-Katz method:WS/T 570-2017[S].2017. [4] 万孝玲,吕国丽,蒋智华,等.2016—2020年广西壮族自治区人群土源性线虫感染监测结果[J].中国寄生虫学与寄生虫病杂志,2021,39(6):800-807. WAN X L,LÜ G L,JIANG Z H,et al.Surveillance on soil-transmitted nematode infections in population in Guangxi Zhuang Autonomous Region during 2016-2020[J].Chin J Parasitol Parasit Dis,2021,39(6):800-807. [5] 王笑笑,姚立农,陈华良,等.浙江省东南山区钩虫感染现况调查[J].预防医学,2021,33(11):1130-1132. WANG X X,YAO L N,CHEN H L,et al.Hookworm infection in southeast area of Zhejiang Province[J].Prev Med,2021,33(11):1130-1132. [6] 曹妍,杨小琼,冉定鑫,等.阆中市农村土源性线虫感染情况调查[J].预防医学,2019,31(6):600-602. CAO Y,YANG X Q,RAN D X,et al.Infection status of soil-transmitted nematode in Langzhong[J].Prev Med,2019,31(6):600-602. [7] 金行一,朱素娟,徐卫民,等.杭州市人体肠道寄生虫病原谱调查分析[J].中国卫生检验杂志,2020,30(19):2409-2412. JIN X Y,ZHU S J,XU W M,et al.Investigation and analysis of pathogenic spectrum of human intestinal parasite in Hangzhou City[J].Chin J Health Lab Technol,2020,30(19):2409-2412. [8] 宋建强,孙明华,许军华,等.海盐县居民土源性线虫感染现况调查[J].预防医学,2017,29(10):1039-1040,1043. SONG J Q,SUN M H,XU J H,et al.Investigation on the prevalence of soil-borne nematode infection in Haiyan County[J].Prev Med,2017,29(10):1039-1040,1043. [9] 金行一,朱素娟,徐卫民,等.2015—2018年杭州市土源性线虫感染调查分析[J].中国寄生虫学与寄生虫病杂志,2019,37(5):608-611. JIN X Y,ZHU S J,XU W M,et al.Survey of soil-transmitted nematode infection in Hangzhou from 2015 to 2018[J].Chin J Parasitol Parasit Dis,2019,37(5):608-611. [10] 金锦燕,严霁霞,王斌,等.宁海县沿海地区土源性线虫感染情况和行为危险因素分析[J].中国农村卫生事业管理,2017,37(11):1354-1356. JIN J Y,YAN J X,WANG B,et al.Soil-borne nematode infection and behavioral risk factors in coastal areas of Ninghai County[J].Chin Rural Health Serv Adm,2017,37(11):1354-1356. [11] 陈沙彬,雷永良,陈秀英,等.丽水市莲都区老竹镇土源性线虫感染现状调查[J].中国卫生检验杂志,2016,26(21):3178-3179,3182. CHEN S B,LEI Y L,CHEN X Y,et al.Investigation of soil-borne nematodes infection in Laozhu,Liandu district of Lishui in 2015[J].Chin J Health Lab Technol,2016,26(21):3178-3179,3182. [12] 崔清荣. 浙江省天台县土源性线虫感染现状调查[J].疾病控制杂志,2005,9(6):671-672. CUI Q R.Investigation on soil-borne nematodes infection in Tiantai County,Zhejiang Province[J].Chin J Dis Control Prev,2005,9(6):671-672. [13] 温春虹,曾智聪,刘将,等.消化内镜诊治寄生虫感染614例分析[J].中国内镜杂志,2019,25(12):71-75. WENG C H,ZENG Z C,LIU J,et al.Analysis of 614 cases of parasite infection diagnosed and treated by gastrointestinal endoscope[J].China J Endosc,2019,25(12):71-75. [14] 李燕榕,谢汉国,陈宝建,等.福建省人体钩虫感染现状调查[J].预防医学,2018,30(11):1081-1084. LI Y R,XIE H G,CHEN B J,et al.Cross-sectional investigation of human hookworm infection in Fujian Province[J].Prev Med,2018,30(11):1081-1084. [15] 袁菊,徐杰,张伟琴.钩虫病误诊1例[J].皮肤病与性病,2020,42(1):97-98. YUAN J,XU J,ZHANG W Q.Misdiagnosis of one hookworm disease case[J].Chin J Misdiagn,2020,42(1):97-98. [16] 谭丹. 重症肺炎并钩虫病致上消化道大出血一例误诊辨析[J].临床误诊误治,2017,30(9):6-7. TAN D.Misdiagnosis and analysis of a case of severe pneumonia complicated by hookworm disease with massive hemorrhage of upper digestive tract[J].Clin Misdiagn Misther,2017,30(9):6-7.
