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预防医学  2022, Vol. 34 Issue (4): 371-374    DOI: 10.19485/j.cnki.issn2096-5087.2022.04.010
  疾病控制 本期目录 | 过刊浏览 | 高级检索 |
南川区居民结核潜伏感染调查
雷蓉蓉1, 张婷1, 吴成果1, 罗建奎2, 汪清雅1, 任昌理2
1.重庆市结核病防治所区县防治科,重庆 400050;
2.重庆市南川区结核病防治所,重庆 408400
Prevalence of latent tuberculosis infections among residents in Nanchuan District
LEI Rongrong1, ZHANG Ting1, WU Chengguo1, LUO Jiankui2, WANG Qingya1, REN Changli2
1. Department of Control and Prevention, Chongqing Institute of Tuberculosis Control and Prevention, Chongqing 400050, China;
2. Nanchuan Institute of Tuberculosis Control and Prevention, Chongqing 408400, China
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摘要 目的 了解重庆市南川区居民结核潜伏感染现状,为制定结核潜伏感染防制措施提供依据。方法 于2020年1—4月,采用多阶段整群随机抽样方法选取南川区1个街道和1个乡镇的居民为调查对象,收集人口学信息、吸烟史、饮酒史、结核病患者接触史和卡痕等资料;采用γ-干扰素释放试验(IGRA)检测结核分枝杆菌感染状态,IGRA检测阳性且排除活动性结核病为结核潜伏感染,分析调查对象结核潜伏感染率。结果 调查1 000人,其中男性381人,女性619人,男女性别比为0.62∶1,年龄为(45.87±18.40)岁。吸烟222人,占22.20%。饮酒247人,占24.70%。有结核病患者接触史62人,占6.20%。有卡痕904人,占90.40%。检出结核潜伏感染198例,感染率为19.80%。男性结核潜伏感染率为23.36%,高于女性的17.61%(χ2=4.911,P=0.027);已婚/离异/丧偶居民结核潜伏感染率为24.22%,高于未婚居民的2.01%(χ2=49.514,P<0.001);吸烟居民结核潜伏感染率为27.93%,高于未吸烟居民的17.48%(χ2=11.871,P=0.001)。结核潜伏感染率随年龄(χ2趋势=59.100,P<0.001)和体质指数(χ2趋势=9.479,P=0.002)的升高呈上升趋势。结论 南川区居民结核潜伏感染率较高,尤其是男性、老年人、高体质指数和吸烟人群。应重视风险监测,及时干预。
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雷蓉蓉
张婷
吴成果
罗建奎
汪清雅
任昌理
关键词 结核潜伏感染结核分枝杆菌重庆市    
AbstractObjective To investigate the current prevalence of latent tuberculosis infection (LTBI) among residents living in Nanchuan District, Chongqing Municipality, so as to provide the evidence for formulating LTBI control measures. Methods The residents living in one street and one township from Nanchuan District were randomly selected using the multistage cluster sampling method during the period between January and April, 2020, and their demographic information, smoking history, history of alcohol consumption, history of contacts with tuberculosis patients and Bacillus Calmette-Guérin ( BCG ) vaccination scars were collected. The infection of Mycobacterium tuberculosis was detected using interferon gamma release assay ( IGRA ), and a positive IGRA test and exclusion of active tuberculosis was defined as LTBI. The prevalence of LTBI was descriptively analyzed among the study subjects. Results Totally 1 000 residents were recruited, including 381 males and 619 females, with a male to female ratio of 0.62∶1. The mean age was ( 45.87±18.40 ) years. Among all participants, there were 222 smokers ( 22.20% ), 247 subjects consuming alcohol (24.70%), 62 subjects with a history of contacts with tuberculosis patients ( 6.20% ) and 904 subjects with BCG scars ( 90.40% ). A total of 198 residents were diagnosed with LTBI (19.80% prevalence), and a higher prevalence rate of LTBI was seen in men than in women ( 23.36% vs. 17.61%; χ2=4.911, P=0.027 ). The prevalence of LTBI was significantly higher in married/divorced/widowed residents than in unmarried residents ( 24.22% vs. 2.01%; χ2=49.514, P<0.001 ), and significantly greater prevalence was found in smokers than in non-smokers ( 27.93% vs. 17.48%; χ2=11.871, P=0.001 ). The prevalence of LTBI appeared a tendency towards a rise with age ( χ2trend=59.100, P<0.001 ) and body mass index ( χ2trend=9.479, P=0.002 ). Conclusions The prevalence of LTBI is high among residents living in Nanchuan District, notably among elder, male smokers with high body mass index. Risk monitoring and timely interventions are required.
Key wordslatent tuberculosis infection    Mycobacterium tuberculosis    Chongqing Municipality
收稿日期: 2021-10-25      修回日期: 2022-01-05      出版日期: 2022-04-10
中图分类号:  R512  
基金资助:“十三五”国家科技重大专项(2017ZX10201302)
通信作者: 任昌理,E-mail:474407264@qq.com   
作者简介: 雷蓉蓉,硕士,副主任医师,主要从事结核病预防控制工作
引用本文:   
雷蓉蓉, 张婷, 吴成果, 罗建奎, 汪清雅, 任昌理. 南川区居民结核潜伏感染调查[J]. 预防医学, 2022, 34(4): 371-374.
LEI Rongrong, ZHANG Ting, WU Chengguo, LUO Jiankui, WANG Qingya, REN Changli. Prevalence of latent tuberculosis infections among residents in Nanchuan District. Preventive Medicine, 2022, 34(4): 371-374.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2022.04.010      或      http://www.zjyfyxzz.com/CN/Y2022/V34/I4/371
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