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预防医学  2018, Vol. 30 Issue (10): 982-986,991    DOI: 10.19485/j.cnki.issn2096-5087.2018.10.003
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杭州市男男性行为人群HIV新发感染及影响因素研究
李西婷,罗艳,张兴亮,金洁,许珂,罗文杰,李清春
杭州市疾病预防控制中心艾防所,浙江 杭州 310021
Incidence and influencing factors for HIV infection among men who have sex with men in Hangzhou
LI Xi-ting,LUO Yan,ZHANG Xing-liang,JIN Jie,XU Ke,LUO Wen-jie,LI Qing-chun
Department of HIV/AIDS and STDs Control and Prevention,Hangzhou Center for Disease Control and Prevention,Hangzhou,Zhejiang 310021,China
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摘要 目的 了解杭州市男男性行为(MSM)人群HIV新发感染情况及影响因素。方法 于2014年9月—2015年9月在杭州市招募523名HIV阴性MSM进行前瞻性队列研究,通过问卷调查收集人口学和行为学信息,并检测HIV抗体和梅毒,每3个月随访一次。以HIV抗体阳转为研究终点事件,计算HIV新发感染率,采用Cox回归模型分析MSM人群HIV新发感染的影响因素。结果 12个月累计随访374人,队列总随访率为71.51%;累计HIV新发感染16例,HIV新发感染率为6.57/100人年。Cox回归分析结果显示:年龄<30岁(HR=10.050,95%CI:2.576~39.212),本地居住时间>2年(HR=0.082,95%CI:0.020~0.341)和近3个月与临时同性性伴肛交时使用安全套(HR=0.060,95%CI:0.019~0.188)是MSM人群新发感染HIV的影响因素。结论 杭州市MSM人群HIV新发感染率较高,年龄<30岁、本地居住时间少于2年、与临时性伴无保护肛交的MSM人群感染HIV的风险升高。
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李西婷
罗艳
张兴亮
金洁
许珂
罗文杰
李清春
关键词 : 艾滋病病毒,  艾滋病,  男男性行为人群,  新发感染    
Abstract:Objective To study HIV incidence and related factors among men who have sex with men(MSM)in Hangzhou. Methods We conducted a prospective cohort study consisted of 523 HIV-negative MSM in Hangzhou.We collected their sociodemographic and behavior information by questionnaire and blood samples for HIV and syphilis detection at baseline and during follow-up period. HIV seroconversion was defined as the end point to calculate the HIV incidence. We analyzed the influencing factors for HIV infection among MSM by cox regression. Results We observed a total of 374 participants for 12 months,accounting for 71.51%. There were 16 HIV positive cases and the HIV incidence rate was 6.57/100 person-years. Multivariate cox regression analysis showed that less than 30 years old(HR=10.050,95%CI:2.576-39.212),living in Hangzhou for more than 2 years(HR=0.082,95%CI:0.020-0.341)and having unprotected anal intercourse with casual male partners in the past 3 months(HR=0.060,95%CI:0.019-0.188)were associated with HIV incidence. Conclusio HIV incidence among MSM in Hangzhou was relatively high. The MSM who were less than 30 years old,living in Hangzhou for less than 2 years and having unprotected anal intercourse with casual male partners have higher risk of HIV infection.
Key words: HIV    AIDS    MSM    Incidence
          出版日期: 2018-09-26
中图分类号:  R512.91  
基金资助:浙江省医药卫生科技计划项目(2015KYA189);杭州市科技局社会发展项目(20160533B51)
作者简介: 李西婷,硕士,副主任技师,主要从事艾滋病性病防制工作
通信作者: 李清春,E-mail:19348710@qq.com   
引用本文:   
李西婷, 罗艳, 张兴亮, 金洁, 许珂, 罗文杰, 李清春. 杭州市男男性行为人群HIV新发感染及影响因素研究[J]. 预防医学, 2018, 30(10): 982-986,991.
LI Xi-ting, LUO Yan, ZHANG Xing-liang, JIN Jie, XU Ke, LUO Wen-jie, LI Qing-chun. Incidence and influencing factors for HIV infection among men who have sex with men in Hangzhou. Preventive Medicine, 2018, 30(10): 982-986,991.
链接本文:  
https://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2018.10.003      或      https://www.zjyfyxzz.com/CN/Y2018/V30/I10/982
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