|
|
|
| Epidemiological characteristics and spatial-temporal clustering of pertussis in Zhoushan City from 2018 to 2024 |
| LI Peng1, LI Qian2, TANG An1, YAN Jianbo1,2
|
1. Zhoushan Center for Disease Control and Prevention (Zhoushan Institute of Public Health Supervision), Zhoushan, Zhejiang 316021, China;
2. School of Public Health, Nanchang University, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang, Jiangxi 330019, China |
|
|
|
|
Abstract Objective To analyze the epidemiological characteristics and spatial-temporal clustering of pertussis in Zhoushan City, Zhejiang Province from 2018 to 2024, so as to provide reference for formulating regional pertussis prevention and control strategies. Methods Data of pertussis cases in Zhoushan City from 2018 to 2024 were collected from the Infectious Disease Reporting Information System of China Disease Prevention and Control Information System. Descriptive epidemiological methods were used to analyze the temporal, population and regional distribution characteristics of pertussis incidence. Spatial autocorrelation and spatial-temporal scan analysis were used to explore the spatial-temporal clustering of pertussis incidence. Results A total of 1 081 pertussis cases were reported in Zhoushan City from 2018 to 2024. The number of reported cases was relatively high in 2024, with 1 070 cases and a reported incidence of 91.22/105, and 859 pertussis cases were reported from April to May 2024, accounting for 80.28% of the annual cases. The number of reported cases was relatively high among the groups aged 5-<10 years, 10-<15 years and ≥15 years, with 682 cases (63.09%), 164 cases (15.17%) and 121 cases (11.19%), respectively. The majority of cases were students and preschool children, with 640 cases (59.20%) and 279 cases (25.81%), respectively. The number of reported cases was relatively high in Putuo District and Dinghai District, with 604 cases (55.87%) and 405 cases (37.47%), respectively, and their average annual reported incidences were 163.36/105 and 73.94/105, respectively. The average annual reported incidence in urban areas was 15.96/105, which higher than the rural areas counterpart of 3.82/105 (P<0.05). Spatial autocorrelation analysis showed a positive spatial correlation for pertussis incidence in 2024 (P<0.05). There were 10 high-high clusters mainly distributed in Baiquan Town, Changguo Subdistrict, Chengdong Subdistrict, Huanan Subdistrict, and Lincheng Subdistrict in Dinghai District; Donggang Subdistrict, Liuheng Town, Shenjiamen Subdistrict, Zhanmao Subdistrict, and Zhujiajian Subdistrict in Putuo District. Spatial-temporal scan analysis identified one Class Ⅰ cluster in 2024, centered on Lincheng Subdistrict in Dinghai District and covering 15 towns (subdistricts), with the clustering period from April 1 to May 5, 2024. Conclusions In Zhoushan City, spring was the high-incidence season from 2018 to 2024; the 5-<10 years age group, students and preschool children were high-incidence populations of pertussis. The risk of pertussis was higher in urban areas, particularly in Lincheng Subdistrict.
|
|
Received: 25 June 2026
Revised: 02 September 2026
Published: 22 September 2026
|
|
|
|
|
|
[1] Wang Y,Lu G S.Global,regional,and national epidemiology of pertussis in children from 1990 to 2021[J/OL].Vaccine,2025,61[2026-09-02].https://doi.org/10.1016/j.vaccine.2025.127378.
[2] 李涛,候立娟,唐继海.百日咳流行现状及免疫策略研究进展[J].安徽预防医学杂志,2023,29(6):492-496.
[3] Liu J,Lu G,Qiao J.Global resurgence of pertussis in infants[J/OL].BMJ,2025,391[2026-09-02].https://doi.org/10.1136/bmj.r2169.
[4] 中华预防医学会,中华预防医学会疫苗与免疫分会,徐爱强,等.中国百日咳行动计划专家共识[J].中华流行病学杂志,2021,42(6):955-965.
[5] 中华人民共和国国家疾病预防控制局. 2024年全国法定传染病疫情概况[EB/OL].[2026-09-02].https://www.ndcpa.gov.cn/jbkzzx/c100016/common/content/content_1998217472895258624.html.
[6] 丁哲渊,杨研,傅天颖,等.2024年浙江省法定传染病疫情分析[J].预防医学,2025,37(5):433-437,442.
[7] 李玲,王黎荔,张欣悦,等.2015—2024年温州市猩红热流行特征和时空聚集性分析[J].预防医学,2025,37(12):1247-1251.
[8] 丁林玲,周洋,朱瑶,等.2024年浙江省百日咳流行特征和住院情况分析[J].中华预防医学杂志,2026,60(5):721-727.
[9] 国家卫生健康委办公厅,国家中医药局综合司.百日咳诊疗方案(2023年版)[J].中国感染控制杂志,2024,23(4):544-546.
[10] Geng Y M,Zhang L L.Impact of non-pharmaceutical interventions during COVID-19 pandemic on pertussis,scarlet fever and hand-foot-mouth disease in China[J].J Infect,2022,84(2):13-15.
[11] 黄洁茹,倪朝荣,王黎荔,等.2005—2023年温州市百日咳流行特征及时空聚集性[J].中国预防医学杂志,2025,26(4):455-460.
[12] 周绍英,郭延波,王建美,等.2015—2024年宁波市百日咳流行特征及时空聚集性分析[J].中国预防医学杂志,2026,27(6):688-693.
[13] Hu Y H,Shi W,Meng Q,et al.Detection of Bordetella spp. in children with pertussis-like illness from 2018 to 2024 in China[J/OL]. J Infect,2024,89[2026-09-02].https://doi.org/10.1016/j.jinf.2024.106222. |
|
|
|
