|
|
|
| Epidemiological characteristics and spatial-temporal clustering of hepatitis E in Jinhua City from 2010 to 2025 |
| ZHANG Tao, BAI Kaizhi, LONG Zhiping, LI Ke, WU Xiaohong, ZHANG Guangming, WANG Zuoyi
|
| Jinhua Center for Disease Control and Prevention, Jinhua, Zhejiang 321000, China |
|
|
|
|
Abstract Objective To analyze the epidemiological characteristics and spatial-temporal clustering of hepatitis E in Jinhua City, Zhejiang Province from 2010 to 2025, so as to provide evidence for formulating targeted hepatitis E prevention and control measures. Methods Data of reported hepatitis E cases in Jinhua City from 2010 to 2025, including gender, age and occupation, were collected through the Epidemiological Investigation System of China Disease Prevention and Control Information System. Descriptive epidemiological methods were used to analyze the temporal, population and regional distribution characteristics of hepatitis E. The average annual percent change (AAPC) was used to analyze the changing trend of reported incidence of hepatitis E. Spatial autocorrelation and spatial-temporal scan analysis were used to analyze the spatial-temporal clustering of hepatitis E. Results A total of 2 555 hepatitis E cases were reported in Jinhua City from 2010 to 2025, with an average annual reported incidence of 2.65/105. The overall trend of reported incidence had no statistical significance (AAPC=-1.233%, 95%CI: -6.027%-3.782%, P>0.05). Cases were reported every month, and the number of reported cases was relatively high from January to May, with 1 302 cases (50.96%). The average annual reported incidence of hepatitis E among males was 3.47/105, which was higher than the female counterpart of 1.73/105 (P<0.05). The number of hepatitis E reported cases was relatively high in the groups aged 40-<50 years and 50-<60 years, with 544 cases (21.29%) and 671 cases (26.26%), respectively. The average annual reported incidence of hepatitis E was relatively high in the groups aged 60-<70 years and 70-<80 years, with 5.18/105 and 4.41/105, respectively. The number of hepatitis E reported cases was relatively high among farmers, with 1 512 cases (59.18%). Lanxi City had a relatively high average annual reported incidence of hepatitis E, at 4.53/105. Hepatitis E in Jinhua City showed positive spatial correlation in 2013, 2014, 2022, 2023 and 2025 (all P<0.05), exhibiting a spatially clustered distribution.The high-high clusters were mainly distributed in some townships (subdistricts) of Wucheng District, Lanxi City, Dongyang City, Pan'an County and Wuyi County. Class Ⅰ cluster of hepatitis E in Jinhua City from 2010 to 2025 was Choucheng Subdistrict of Yiwu City, with the clustering period from January 2011 to December 2018. Conclusions The reported incidence of hepatitis E in Jinhua City remained at a moderate level, with a gentle overall trend from 2010 to 2025. Hepatitis E peaked in winter and spring. Males, middle-aged and elderly people, and farmers were high-risk populations. Lanxi City and Yiwu City were high-risk areas.
|
|
Received: 22 May 2026
Revised: 31 August 2026
Published: 22 September 2026
|
|
|
|
|
|
[1] Songtanin B,Molehin A J,Brittan K,et al.Hepatitis E virus infections:epidemiology,genetic diversity,and clinical considerations[J/OL].Viruses,2023,15(6)[2026-08-31].https://doi.org/10.3390/v15061389.
[2] World Health Organization.Hepatitis E[EB/OL].[2026-08-31].https://www.who.int/news-room/fact-sheets/detail/hepatitis-e.
[3] 董邓波,邹圣强,唐舒.2009—2019年中国病毒型肝炎发病的时空流行病学特征分析[J].现代预防医学,2024,51(4):595-601.
[4] 唐晓倩,王瑞,张川,等.2008—2023年浙江省戊型肝炎流行特征和时空聚集性研究[J].中华流行病学杂志,2025,46(5):789-795.
[5] 黄澳迪,唐林,王晓琪,等.中国2011—2021年戊型病毒性肝炎发病趋势和时空聚集性[J].中国疫苗和免疫,2022,28(4):417-421.
[6] Tan J,Chen Y J,Wang L,et al.Acute sporadic hepatitis E in the Zhejiang coastal area of China:a 14-year hospital-based surveillance study[J/OL].Virol J,2019,16(1)[2026-08-31].https://doi.org/10.1186/s12985-019-1119-7.
[7] 刘明奇,马岩,郑莹颖,等.2006—2024年绍兴市戊型病毒性肝炎流行特征[J]. 预防医学,2025,37(11):1155-1159.
[8] 富小飞,刘砚清,胡洁,等.2005—2021年嘉兴市甲型病毒性肝炎和戊型病毒性肝炎流行特征分析[J].预防医学,2023,35(9):737-740.
[9] 黄洁茹,倪朝荣,王黎荔,等.2004—2023年温州市戊型肝炎流行特征及时空聚集性分析[J].中国预防医学杂志,2025,26(7):850-855.
[10] 张海荣,林志强,吴瑞红,等.2014—2023年福建省戊型病毒性肝炎流行趋势和时空聚集性[J].中华疾病控制杂志,2024,28(11):1361-1364.
[11] 赵敏,彦子博.2010—2022年黑龙江省戊型病毒性肝炎流行病学特征分析[J].现代预防医学,2025,52(6):1019-1023,1043.
[12] Yang M,Cheng X Q,Zhao Z Y,et al.Feasibility of controlling hepatitis E in Jiangsu Province,China:a modelling study[J/OL].Infect Dis Poverty,2021,10(1)[2026-08-31].https://doi.org/10.1186/s40249-021-00873-w.
[13] 章伟,周印.2013—2022年镇江市戊型病毒性肝炎流行病学特征[J].江苏预防医学,2024,35(5):646-647,650.
[14] 刘正楠,倪兆林,赵秋芳,等. 2004—2022年玉溪市病毒性肝炎流行趋势分析[J].预防医学,2023,35(12):1075-1079. |
|
|
|
