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预防医学  2016, Vol. 28 Issue (2): 132-135    
  论 著 本期目录 | 过刊浏览 | 高级检索 |
蒙得维的亚沙门菌耐药性分析
钱秀芬, 李克诚
瑞安市人民医院,浙江瑞安 325200
An analysis on the drug resistance of salmonella montevideo
QIAN Xiu-fen, LI Ke-cheng
The Affiliated Third Hospital of Wenzhou College,Rui' an,Wenzhou, Zhejiang, 325200,China
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摘要 目的 了解蒙得维的亚沙门菌的药物敏感性,指导临床合理使用抗生素。方法 回顾性分析瑞安市人民医院2011—2014年分离的蒙得维的亚沙门菌,并对其作抗菌药物耐药性试验。结果 31 972份腹泻患者粪便分离蒙得维的亚沙门菌株97株,阳性率为0.30%。不同年龄组患者阳性率比较差异有统计学意义(P<0.01)。其中≤14岁患儿阳性率为0.44%,高于>14岁患者的阳性率0.10%(P<0.01)。蒙得维的亚沙门菌以7月份阳性率最高为1.02%,应用圆形分布法显示7月18日为发病高峰日(P<0.05)。≤14岁患儿的84株蒙得维的亚沙门菌对庆大霉素、萘啶酸、氨苄西林、四环素和头孢唑啉耐药率在52.38%~100.00%之间,>14岁患者的13株蒙得维的亚沙门菌对四环素、氨苄西林、萘啶酸和庆大霉素和头孢唑啉的耐药率在38.46%~100.00%之间,逐项比较,差异均无统计学意义(P>0.05)。结论 该菌对头孢唑啉、萘啶酸和庆大霉素等耐药性较高,在≤14岁和>14岁组患者的蒙得维的亚沙门菌药物耐药性略有不同。
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关键词 蒙得维的亚沙门菌耐药性敏感性分析    
AbstractObjective To learn the antibiotic susceptibility of Salmonella montevideo, and to guide the reasonable clinical use of antibiotics.Methods Drug susceptibility of 97 strains of salmonella montevideo in Rui'an hospital from JAN 1,2011 to DEC 30,2014 were analyzed retrospectively.Results A total of 97 strains were isolated from 31 972 faeces of diarrhea patients, and the positive detection rate was 0.30%. There were significant difference on the positive detection rate among different age group(P<0.01).The positive detection rate of children≤14 was 0.44%, higher than those >14 (P<0.05).July 18 reached the peak of positive detection day using circular distribution method(P<0.05).In children group(n=84),the salmonella montevideo strain were sensitive to the third and fourth-generation cephalosporin,quinolones and aztreonam(88.09%-100%).The drug sensitive rate of salmonella montevideo strain was 47.62% to tetracycline, 30.95% to ampicillin, 15.48% to gentamyoin and 0.00% to cefazolin. In >14 years old group(n=13),the salmonella Montevideo strain were sensitive to the third and fourth-generation cephalosporin, quinolones and aotreonam(88.66%-100%).The drug sensitive rate of salmonella wentevideo strain was 49.48% to tetracycline, 32.98% to ampicillin,15.46% to gentamycin and 0.00% to cefazolin.Conclusion The drug sensitivity of salmonella montevideo to antibiotics had significant difference between ≤14 age group and >14 age group .It is necessary to monitor the change of drug resistance to guide the reasonable clinical use of antibiontics. The third and fourth-generation cephalosporins or quinolones canld be used as clinical treatment.
Key wordsSalmonella montevideo    Drug resistance    Sensitivity    Analysis
收稿日期: 2015-07-14           出版日期: 2016-02-10
中图分类号:  R378.2+2  
作者简介: 钱秀芬,本科,副主任护师,主要从事门诊护理工作
通信作者: 钱秀芬,E-mail:289343219@qq.com   
引用本文:   
钱秀芬, 李克诚. 蒙得维的亚沙门菌耐药性分析[J]. 预防医学, 2016, 28(2): 132-135.
QIAN Xiu-fen, LI Ke-cheng. An analysis on the drug resistance of salmonella montevideo. Preventive Medicine, 2016, 28(2): 132-135.
链接本文:  
https://www.zjyfyxzz.com/CN/      或      https://www.zjyfyxzz.com/CN/Y2016/V28/I2/132
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