Please wait a minute...
文章检索
预防医学  2022, Vol. 34 Issue (8): 821-825    DOI: 10.19485/j.cnki.issn2096-5087.2022.08.013
  疾病控制 本期目录 | 过刊浏览 | 高级检索 |
海宁市居民血脂异常的影响因素分析
陶寄1, 盛敏阳1, 许云峰1, 孙品晶1, 钟节鸣2, 王小花1
1.海宁市疾病预防控制中心慢性病防制科,浙江 海宁 314400;
2.浙江省疾病预防控制中心,浙江 杭州 310051
Factors affecting dyslipidemia among residents in Haining City
TAO Ji1, SHENG Minyang1, XU Yunfeng1, SUN Pinjing1, ZHONG Jieming2, WANG Xiaohua1
1. Department of Non-communicable Disease Control and Prevention, Haining Center for Disease Control and Prevention, Haining, Zhejiang 314400, China;
2. Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China
全文: PDF(859 KB)  
输出: BibTeX | EndNote (RIS)      
摘要 目的 了解浙江省海宁市居民血脂异常患病情况及影响因素,为血脂异常防制提供依据。方法 采用多阶段分层整群抽样方法抽取海宁市5个乡镇(街道)的1 953名15~69岁居民为调查对象,收集人口学资料、吸烟、饮酒、家族史和慢性病患病情况;测量身高、体重、腰围和血压;检测空腹血糖、血尿酸和血脂水平;分析居民血脂异常患病率,采用2020年第七次全国人口普查数据进行标化;采用多因素logistic回归模型分析血脂异常的影响因素。结果 有效调查1 893人,其中男性949人,占50.13%;女性944人,占49.87%;年龄为(47.90±14.34)岁。检出血脂异常513例,血脂异常患病率为27.10%,标化患病率为27.01%;高三酰甘油血症、高胆固醇血症、高低密度脂蛋白胆固醇血症和低高密度脂蛋白胆固醇血症检出率分别为16.53%、3.22%、1.74%和15.27%。多因素logistic回归分析结果显示,男性(OR=1.571,95%CI:1.268~1.947)、脑卒中家族史(OR=1.645,95%CI:1.192~2.270)、高尿酸血症(OR=1.809,95%CI:1.370~2.388)、中心性肥胖(OR=1.423,95%CI:1.066~1.900)、肥胖(OR=1.736,95%CI:1.335~2.257)和体重过低(OR=0.171,95%CI:0.049~0.593)与血脂异常存在统计学关联。结论 海宁市15~69岁居民血脂异常患病率低于全国水平,以高三酰甘油血症和低高密度脂蛋白胆固醇血症为主。男性、肥胖、有脑卒中家族史和高尿酸血症者血脂异常患病风险较高。
服务
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章
陶寄
盛敏阳
许云峰
孙品晶
钟节鸣
王小花
关键词 血脂异常肥胖血糖血尿酸    
AbstractObjective To investigate the prevalence and risk factors of dyslipidemia among residents in Haining City, Zhejiang Province, so as to provide into the management of dyslipidemia. Methods Totally 1 953 residents at ages of 15 to 69 years were recruited using a multi-stage stratified cluster sampling method in 5 townships (streets) of Hainan City. Subjects' demographic features, smoking status, alcohol consumption, family history of diseases and development of chronic diseases were collected. The height, body weight, waist circumstance and blood pressure were measured, and the fasting blood glucose, serum uric acid and blood lipid levels were determined. The prevalence of dyslipidemia was analyzed and standardized by the 7th population census data. The factors affecting dyslipidemia were identified using a multivariable logistic regression model. Results Totally 1 893 valid questionnaires were recovered. The respondents included 949 males (50.13%) and 944 females (49.87%), and had a mean age of (47.90±14.34) years. A total of 513 participants were detected with dyslipidemia, and the prevalence and standardized prevalence of dyslipidemia were 27.10% and 27.01%, respectively. The prevalence of hypertriglyceridemia, hypercholesterolemia, hyperlipoproteinemia and hypolipoproteinemia was 16.53%, 3.22%, 1.74% and 15.27%, respectively. Multivariate logistic regression analysis showed that male (OR=1.571, 95%CI: 1.268-1.947), family history of stroke (OR=1.645, 95%CI: 1.192-2.270), hyperuricemia (OR=1.809, 95%CI: 1.370-2.388), central obesity (OR=1.423, 95%CI: 1.066-1.900), obesity (OR=1.736, 95%CI: 1.335-2.257), underweight (OR=0.171, 95%CI: 0.049-0.593) significantly correlated with dyslipidemia. Conclusions The prevalence of dyslipidemia is lower than the national level among residents at ages of 15 to 69 years in Haining City, and hypertriglyceridemia and hypolipoproteinemia are predominant types of dyslipidemia. Male, obesity, family history of stroke and hyperuricemia are risk factors of dyslipidemia.
Key wordsdyslipidemia    obesity    blood glucose    serum uric acid
收稿日期: 2022-04-20      修回日期: 2022-06-07      出版日期: 2022-08-10
中图分类号:  R195  
基金资助:海宁市科技计划项目(2019043,2019032)
作者简介: 陶寄,硕士,医师,主要从事慢性病预防和控制工作
通信作者: 王小花,E-mail:zjhncdcwxh @163.com   
引用本文:   
陶寄, 盛敏阳, 许云峰, 孙品晶, 钟节鸣, 王小花. 海宁市居民血脂异常的影响因素分析[J]. 预防医学, 2022, 34(8): 821-825.
TAO Ji, SHENG Minyang, XU Yunfeng, SUN Pinjing, ZHONG Jieming, WANG Xiaohua. Factors affecting dyslipidemia among residents in Haining City. Preventive Medicine, 2022, 34(8): 821-825.
链接本文:  
https://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2022.08.013      或      https://www.zjyfyxzz.com/CN/Y2022/V34/I8/821
[1] GBD 2019 Diseases and Injuries Collaborators.Global burden of 369 diseases and injuries in 204 countries and territories,1990-2019:a systematic analysis for the Global Burden of Disease Study 2019[J].Lancet,2020,396(10258):1204-1222.
[2] MAKI K C.The ODYSSEY outcomes trial:clinical implications and exploration of the limits of what can be achieved through lipid lowering[J].J Clin Lipidol,2018,12(5): 1102-1105.
[3] 世界华人检验与病理医师协会.血脂异常疾病检验诊断报告模式专家共识[J].中华医学杂志,2018,98(22):1739-1742.
[4] 张洁,何青芳,王立新,等.浙江省成年人血脂异常知晓率、治疗率和控制率的影响因素分析[J].预防医学,2020,32(12):1230-1235.
ZHANG J,HE Q F,WANG L X,et al.Influencing factors for the awareness,treatment and control rates of dyslipidemia among adults in Zhejiang Province[J].Prev Med,2020,32(12):1230-1235.
[5] 施明明,张晓,李娜,等.居民血脂异常影响因素的列线图分析[J].预防医学,2019,31(5):460-464.
SHI M M,ZHANG X,LI N,et al.Establishment of nomogram for dyslipidemia related factors[J].Prev Med,2019,31(5):460-464.
[6] 中国成人血脂异常防治指南修订联合委员会. 中国成人血脂异常防治指南 (2016 年修订版)[J]. 中华健康管理学杂志,2017,11(1):7-28.
Joint Committee Issued Chinese Guideline for the Management of Dyslipidemia in Adults.2016 Chinese guideline for the managementof dyslipidemia in adults[J]. Chin J Health Manag,2017,11(1):7-28.
[7] 中华医学会内分泌学分会.中国高尿酸血症与痛风诊疗指南(2019)[J].中华内分泌代谢杂志,2020,36(1):1-13.
Chinese Society of Endocrinology,Chinese Medical Association.Guideline for the diagnosis and management of hyperuricemia and gout in China(2019)[J].Chin J Endocrinol Metab,2020,36(1):1-13.
[8] 中国高血压防治指南修订委员会.中国高血压防治指南(2018年修订版)[J].中国心血管杂志,2019,24(1):24-56.
Writing Group of 2018 Chinese Guidelines for the Management of Hypertension.2018 Chinese guidelines for the management of hyper-tension of 2018 Chinese Guidelines for the Management of Hypertension.2018 Chinese guidelines for the management of hyper-tension[J].Chin J Cardiol,2019,24(1):24-56.
[9] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2020年版)[J].中华糖尿病杂志,2021,13(4):315-409.
Chinese Diabetes Society.Guideline for the prevention and treatment of type 2 diabetes mellitus in China(2020 edition)[J].Chin J Diabetes Mellit,2021,13(4):315-409
[10] 中华人民共和国卫生部. 中国成人超重和肥胖症预防控制指南[M]. 北京:人民卫生出版社,2006.
Ministry of Health of the People's Republic of China.Guidelines for the prevention and control of overweight and obesity in adults in China[M].Beijing:People's Medical Publishing House,2006.
[11] 苏颖亚. 海宁市2013年农村成人肥胖与血脂异常流行病学调查[J].中国乡村医药,2017,24(5):71-72.
SU Y Y.Epidemiological investigation on obesity and dyslipidemia among rural adults in Haining City in 2013[J].Chin J Rural Med Pharm,2017,24(5):71-72.
[12] 陈伟伟,高润霖,刘力生,等.《中国心血管病报告2017》概要[J].中国循环杂志,2018,33(1):1-8.
CHEN W W,GAO R L,LIU L S,et al.Essentials of the report on cardiovascular diseases in China(2017)[J].Chin Circ J,2018,33(1):1-8.
[13] 李辉,段东辉,王永,等.宁波市居民血脂异常及影响因素分析[J].预防医学,2019,31(5):474-477,481.
LI H,DUAN D H,WANG Y,et al.Prevalence of dyslipidemia and its influence factors amomg residents in Ningbo City[J].Prev Med,2019,31(5): 474-477,481.
[14] 李剑虹,王丽敏,李镒冲,等.2010年我国成年人血脂异常流行特点[J].中华预防医学杂志,2012,46(5): 414-418.
LI J H,WANG L M,LI Y C,et al.Epidemioiogic characteristics of dyslipidemia in Chinese adults in 2010[J].中华预防医学杂志,2012,46(5): 414-418.
[15] ABI-AYAD M,ABBOU A,ABI-AYAD F Z,et al.HDL-C,ApoA1 and VLDL-TG as biomarkers for the carotid plaque presence in patients with metabolic syndrome[J].Diabetes Metab Syndr,2018,12(2): 175-179.
[16] 孟焕,邱琳,飒日娜,等.陕西省成人血脂异常流行现状及相关因素研究[J].中国慢性病预防与控制,2021,29(10):750-755.
MENG H,QIU L,SA R N,et al.Prevalance and related factors of dyslipidemia among adults of Shaanxi Province[J].Chin J Prev Contr Chron Dis,2021,29(10): 750-755.
[17] LIMA W G,MARTINS-SANTOS M E S,CHAVES V E.Uric acid as a modulator of glucose and lipid metabolism[J].Biochimie,2015,116:17-23.
[18] ALI N,RAHMAN S,ISLAM S,et al.The relationship between serum uric acid and lipid profile in Bangladeshi adults[J/OL].BMC Cardiovasc Disord,2019,19(1)[2022-06-07].https://doi.org/10.1186/s12872-019-1026-2.
[19] WASYLENKO T M,AHN W S,STEPHANOPOULOS G.The oxidative pentose phosphate pathway is the primary source of NADPH for lipid overproduction from glucose in Yarrowia lipolytica[J].Metab Eng,2015,30(7):27-39.
[20] 井丽,田园梦,林敏,等.辽宁省城市40岁及以上居民血脂异常流行现况及其危险因素分析[J].现代预防医学,2021,48(15):2696-2699,2725.
JIN L,TIAN Y M,LIN M,et al.The prevalance and risk factors of dyslipidemia among residents aged 40 and over in cities,Liaoning[J].Mod Prev Med,2021,48(15): 2696-2699,2725.
[21] 丁贤彬,许杰,唐文革,等.重庆市35岁及以上居民血脂异常患病率及相关因素分析[J].实用预防医学,2021,28(4):412-417.
DING X B,XU J,TANG W G,et al.Prevalence rate of dyslipidemia and its related factors among residents aged 35 years and above in Chongqing Municipality[J].Pract Prev Med,2021,28(4):412-417.
[22] 周仲芳,黄素琼,王小红,等.泸州地区体检在职人群血脂异常流行情况及危险因素分析[J].现代预防医学,2021,48(21):3990-3995.
ZHOU Z F,HUANG S Q,WANG X H,et al.Analysis of the prevalacne and risk factors of dyslipidemia in the working population of physical examination in Luzhou[J].Mod Prev Med,2021,48(21): 3990-3995.
[1] 高慧, 谢亮, 姚春阳, 王林红, 金鎏, 胡洁. 血脂异常患者社区综合管理模式的干预效果评价[J]. 预防医学, 2026, 38(1): 15-19.
[2] 郭艳强, 张丽, 张兰, 韩荣荣. 高血压患者肥胖类型与动脉粥样硬化性心血管疾病风险的关系研究[J]. 预防医学, 2026, 38(1): 36-42.
[3] 贾梦涵, 陈培, 李鑫, 孙玲. 食品环境与肥胖的相关性研究进展[J]. 预防医学, 2026, 38(1): 43-47.
[4] 高雷, 叶真, 王玮, 赵栋, 徐沛维, 章荣华. 生命早期肥胖原暴露与儿童肥胖关系的研究进展[J]. 预防医学, 2026, 38(1): 48-54.
[5] 王芸, 申赟魁, 刘博昊, 陈静, 张琨. 延庆区中小学生近视与超重肥胖共患现况调查[J]. 预防医学, 2026, 38(1): 85-88.
[6] 陆杰, 张柯, 吴雅, 王玥, 张玥, 陆叶, 吴周理, 任志华, 黄艺文. 肥胖指标预测2型糖尿病患者心脑血管疾病的效果比较[J]. 预防医学, 2025, 37(9): 886-891.
[7] 张一, 李梦迪, 石亚锋, 苗超. 余姚市中小学生超重和肥胖现况调查[J]. 预防医学, 2025, 37(9): 955-958.
[8] 周梦怡, 苏丹婷, 何梦洁, 徐沛维, 韩丹, 黄李春, 章荣华. 植物性饮食与不同肥胖类型的关联研究[J]. 预防医学, 2025, 37(8): 773-778.
[9] 黄阳梅, 沈旭娟, 谢董颖, 张琦, 郑子聪, 王勐. 小学生体重监测信息反馈干预的效果评价[J]. 预防医学, 2025, 37(6): 541-545.
[10] 俞丹丹, 杨加丽, 张雅萍, 许慧琳, 何丹丹, 李俊. 2型糖尿病共病患者空腹血糖波动轨迹的影响因素研究[J]. 预防医学, 2025, 37(6): 562-567,572.
[11] 陆丽君, 袁磊, 李殿江, 卢昆, 朱怡萱, 王志勇, 刘思浚. 老年2型糖尿病患者自我效能、自我管理行为在抑郁症状与血糖控制间的中介效应分析[J]. 预防医学, 2025, 37(5): 455-459.
[12] 蒋安然, 朱煜典, 鲁芬, 方大春, 翟光富. 膳食行为与中学生超重肥胖的关联研究[J]. 预防医学, 2025, 37(4): 341-345.
[13] 陈海苗, 马岩, 刘明奇, 马珊珊, 李军, 方益荣. 儿童期肥胖与2型糖尿病、冠心病的孟德尔随机化研究[J]. 预防医学, 2025, 37(3): 307-311.
[14] 江南, 唐晓敏, 孙文韬. 膳食模式与中小学生超重肥胖的关联研究[J]. 预防医学, 2025, 37(3): 228-232.
[15] 米孝濛, 熊苏婷, 徐文国, 徐文超. 常州市35岁及以上居民血脂异常调查[J]. 预防医学, 2025, 37(2): 173-177.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed