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预防医学  2018, Vol. 30 Issue (2): 167-169    DOI: 10.19485/j.cnki.issn2096-5087.2018.02.014
  论著 本期目录 | 过刊浏览 | 高级检索 |
医务人员维生素D水平与血脂的相关性研究
范吉星, 陈狄
北京积水潭医院社区保健科,北京 100035
Correlation between serum vitamin D level and dyslipidaemias in medical staff
FAN Ji-xing, CHEN Di
Community Care Division,Beijing Jishuitan Hospital,Beijing 100035,China
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摘要 目的 探讨医务人员维生素D水平与血脂的相关性。方法 于2015年纳入在某三甲医院体检的754名医务人员为研究对象,抽取静脉血检测25(OH)D和血生化指标等,并分析25(OH)D与血脂相关指标水平的相关性。结果 754名医务人员的血清25(OH)D平均为(15.94±7.41)ng/mL,其中维生素D严重缺乏156人,占20.69%;维生素D缺乏418人,占57.89%;维生素D不足147人,占19.50%;维生素D充足33人,占4.38%。相关分析结果显示,校正性别、年龄后,25(OH)D分别与体质指数(BMI)(r=-0.090,P=0.013)、总胆固醇(TC)(r=-0.309,P<0.001)、三酰甘油(TG)(r=-0.079,P=0.030)、低密度脂蛋白(LDL-C)(r=-0.143,P<0.001)呈负相关,与高密度脂蛋白(HDL-C)(r=0.004,P=0.922)、尿酸(UA)(r=-0.024,P=0.504)和空腹血糖(FPG)(r=-0.048,P=0.187)未见统计学关联。多重线性回归分析结果 显示,25(OH)D与TC呈负相关(β'=-0.298,P<0.001)。结论 医务人员维生素D缺乏状况较为普遍,需引起重视;维生素D缺乏与TC升高呈负相关。
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范吉星
陈狄
关键词 维生素D医务人员血脂相关性分析    
AbstractObjective To explore the relationship between low serum vitamin D levels and dyslipidaemias in medical staff. Methods A total of 754 medical staff that get physical examination in our hospital were enrolled in this study. Venous blood samples were obtained,then serum 25(OH)D and lipids level were measured. Then the blood biochemical indexes of medical staff with different levels of vitamin D were compared and the correlation between 25(OH)D and blood lipid related biochemical indexes were analyzed. Results The average serum 25(OH)D in the 754 subjects was(15.94±7.41)ng/mL. Patients in severe vitamin D deficient group were 156(20.69%),and in vitamin D deficient group were 418(57.89%),as well as in vitamin D inadequate group were 147(19.50%)and in vitamin D adequate group were 33(4.38%). After adjustment of age and gender,a significantly negative correlation was found between 25(OH)D and BMI(r=-0.090,P=0.013),TC(r=-0.309,P<0.001),TG(r=-0.079,P=0.030)and LDL-C(r=-0.143,P<0.001). Further multivariate linear regression analysis showed that TC was negatively correlated with vitamin D(β'=-0.298,P<0.001). Conclusion Vitamin D deficiency is very common among medical staff and we should pay attention to this condition. Vitamin D deficiency is related to the increasing of serum TC.
Key wordsVitamin D    Medical staff    Dyslipidemia    Correlation analysis
收稿日期: 2017-07-25      出版日期: 1900-01-01
ZTFLH:  R591.44  
通信作者: 陈狄,E-mail:chendi_jst@163.com   
作者简介: 范吉星,博士,医师,主要从事骨质疏松防治研究工作
引用本文:   
范吉星, 陈狄. 医务人员维生素D水平与血脂的相关性研究[J]. 预防医学, 2018, 30(2): 167-169.
FAN Ji-xing, CHEN Di. Correlation between serum vitamin D level and dyslipidaemias in medical staff. Preventive Medicine, 2018, 30(2): 167-169.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2018.02.014      或      http://www.zjyfyxzz.com/CN/Y2018/V30/I2/167
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