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预防医学  2021, Vol. 33 Issue (10): 973-976,982    DOI: 10.19485/j.cnki.issn2096-5087.2021.10.001
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浙江省居民膳食烟酸摄入量与代谢综合征的关联研究
贾成静1,沈郁2,苏丹婷2,王蒙2,黄李春2,胡崇高2
1.宁波大学医学院,浙江 宁波 315210;
2.浙江省疾病预防控制中心
Association of dietary niacin intake with metabolic syndromeamong adults in Zhejiang Province
JIA Chengjing*, SHEN Yu, SU Danting, WANG Meng, HUANG Lichun, HU Chonggao
*Medical School of Ningbo University, Ningbo, Zhejiang 315210, China
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摘要 目的 分析浙江省居民膳食烟酸摄入量与代谢综合征(MS)的关联性,为MS的膳食干预提供参考。方法 采用多阶段整群随机抽样方法,选择杭州市下城区、宁波市奉化市和温州市苍南县等10个县(市、区)≥18岁常住居民为调查对象。采用中国疾病预防控制中心制定的调查问卷收集一般情况;测量腰围、血压、血糖和血脂等;采用连续3天24小时膳食回顾法记录每人每天食物摄入量,计算烟酸和能量摄入量,并按烟酸摄入量四分位数分组(Q1、Q2、Q3和Q4)。采用多因素Logistic回归模型分析烟酸摄入量与MS及其组分异常风险的关联。结果 共调查2 438人,检出MS 871例,检出率为35.73%。烟酸摄入量的M(QR)为11.75(5.72)mg/d。多因素Logistic回归分析结果显示,与烟酸摄入量Q1组比较,Q2组(OR=0.741,95%CI:0.561~0.978)和Q4组(OR=0.679,95%CI:0.487~0.947)MS风险降低;Q2组(OR=0.688,95%CI:0.516~0.919)和Q4组(OR=0.678,95%CI:0.479~0.960)中心性肥胖风险降低;Q4组(OR=0.721,95%CI:0.536~0.969)高血糖风险降低。按性别分层,与烟酸摄入量Q1组比较,女性Q2组(OR=0.664,95%CI:0.453~0.972)和Q3组(OR=0.646,95%CI:0.432~0.965)MS风险降低;女性Q2组(OR=0.667,95%CI:0.460~0.967)和Q3组(OR=0.607,95%CI:0.408~0.902)中心性肥胖风险降低;男性Q2组(OR=1.836,95%CI:1.202~2.805)低高密度脂蛋白胆固醇风险增加。结论 烟酸摄入量与MS、中心性肥胖和高血糖风险有关。
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贾成静
沈郁
苏丹婷
王蒙
黄李春
胡崇高
关键词 烟酸代谢综合征高血糖中心性肥胖膳食摄入    
AbstractObjective To explore the association of dietary niacin intake and metabolic syndrome ( MS ) and its components among adults in Zhejiang Province, so as to provide the reference for dietary intervention of MS. Methods Using the multi-stage cluster random sampling method, the permanent residents aged 18 years and above were selected and investigated by a questionnaire developed by China Center for Disease Control and Prevention. Their waist circumference, blood pressure, glucose and lipid were measured. The daily dietary niacin intake of each person were calculated by "24-hour dietary review for 3 consecutive days", and divided into Q1, Q2, Q3 and Q4 groups according to quartiles. The multivariate logistic regression model was used to analyze the association of niacin intake with the risks of MS and its components. Results Among 2 438 participants, 871 cases with MS were detected, with a detection rate of 35.73%. The multivariate logistic regression analysis showed that compared with niacin intake Q1 group, Q2 ( OR=0.741, 95%CI: 0.561-0.978 ) and Q4 group ( OR=0.679, 95%CI: 0.487-0.947 ) had a lower risk of MS, Q2 ( OR=0.688, 95%CI: 0.516-0.919 ) and Q4 group ( OR=0.678, 95%CI: 0.479-0.960 ) had a lower risk of abdominal obesity, Q4 group ( OR=0.721, 95%CI: 0.536-0.969 ) had a lower risk of hyperglycemia. Further stratificating by gender, compared with niacin intake Q1 group, Q2 ( OR=0.664, 95%CI: 0.453-0.972 ) and Q3 group ( OR=0.646, 95%CI: 0.432-0.965 ) in women had a lower risk of MS, Q2 (OR=0.667, 95%CI: 0.460-0.967) and Q3 group ( OR=0.607, 95%CI: 0.408-0.902 ) had a lower risk of abdominal obesity; Q2 group ( OR=1.836, 95%CI: 1.202-2.805 ) in men had a higher risk of low high-density lipoprotein cholesterol. Conclusion Niacin intake is associated with an increased risk of MS, abdominal obesity and hyperglycemia.
Key wordsniacin    metabolic syndrome    hyperglycemia    abdominal obesity    dietary intake
          出版日期: 2021-10-10
中图分类号:  R195  
基金资助:科技基础资源调查专项(2017FY101100)
通信作者: 胡崇高,E-mail:chghu@cdc.zj.cn   
作者简介: 贾成静,硕士在读,主要从事营养流行病学研究工作
引用本文:   
贾成静, 沈郁, 苏丹婷, 王蒙, 黄李春, 胡崇高. 浙江省居民膳食烟酸摄入量与代谢综合征的关联研究[J]. 预防医学, 2021, 33(10): 973-976,982.
JIA Chengjing, SHEN Yu, SU Danting, WANG Meng, HUANG Lichun, HU Chonggao. Association of dietary niacin intake with metabolic syndromeamong adults in Zhejiang Province. Preventive Medicine, 2021, 33(10): 973-976,982.
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http://www.zjyfyxzz.com/CN/10.19485/j.cnki.issn2096-5087.2021.10.001      或      http://www.zjyfyxzz.com/CN/Y2021/V33/I10/973
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